转移性肾细胞癌中疑似免疫检查点抑制剂诱导的肺部结节病反应
Suspected immune checkpoint inhibitor-induced pulmonary sarcoid reaction in metastatic renal cell carcinoma.
作者信息
Purcell Victoria, Preti Beatrice, Fernandes Ricardo
机构信息
Schulich School of Medicine and Dentistry Western University London Ontario Canada.
Division of Medical Oncology, Department of Oncology, Schulich School of Medicine & Dentistry Western University London Ontario Canada.
出版信息
Clin Case Rep. 2022 Jul 11;10(7):e5960. doi: 10.1002/ccr3.5960. eCollection 2022 Jul.
We present the case of a 50-year-old male patient with metastatic clear cell renal cell carcinoma (mRCC) who developed a diffuse pulmonary opacification and lymphadenopathy during nivolumab maintenance therapy. This was diagnosed as presumed sarcoid granulomatous inflammatory reaction secondary to immunotherapy, which resolved with holding off therapy and the nivolumab was resumed.
我们报告了一例50岁男性转移性透明细胞肾细胞癌（mRCC）患者，该患者在纳武单抗维持治疗期间出现弥漫性肺混浊和淋巴结病。这被诊断为推测是免疫治疗继发的结节病样肉芽肿性炎症反应，通过暂停治疗得以缓解，随后恢复使用纳武单抗。
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