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单核血细胞镁含量测定的现状

Status of the mononuclear blood cell magnesium assay.

作者信息

Elin R J

出版信息

J Am Coll Nutr. 1987 Apr;6(2):105-7. doi: 10.1080/07315724.1987.10720166.

DOI:10.1080/07315724.1987.10720166
PMID:3584730
Abstract

The tenth anniversary for the determination of magnesium in MBC shows progress, but fundamental questions are still unanswered. Uniformity of the methodology for the assay and the units for reporting the result is a key factor for the validity and comparability of results. There is relatively good agreement among investigators for the mean value of magnesium in MBC expressed with three different units. The MBC magnesium results do not correlate with serum or red blood cell magnesium concentrations in humans. There may be a correlation for magnesium between MBC and muscle and between magnesium and potassium in MBC. The correlation for magnesium between MBC and muscle or other body tissues, particularly bone, needs to be defined for the clinical utility of the assay. A number of studies to date suggest a possible clinical utility for the MBC magnesium assay in several disease entities. Thus, the MBC magnesium assay has come a long way in a relatively short time. The future for the assay is uncertain but does hold hope that this relatively simple test can provide useful information about intracellular or total body magnesium status.

摘要

MBC 中镁测定的十周年回顾显示出了进展,但一些基本问题仍未得到解答。测定方法的一致性以及结果报告的单位是结果有效性和可比性的关键因素。研究人员对于用三种不同单位表示的 MBC 中镁的平均值有相对较好的共识。MBC 中的镁含量结果与人体血清或红细胞中的镁浓度不相关。MBC 中镁与肌肉之间以及镁与钾之间可能存在相关性。为了该测定的临床应用,需要明确 MBC 中镁与肌肉或其他身体组织(特别是骨骼)之间的相关性。迄今为止的多项研究表明,MBC 镁测定在几种疾病实体中可能具有临床应用价值。因此,MBC 镁测定在相对较短的时间内已经取得了长足的进步。该测定的未来尚不确定,但确实有希望这种相对简单的测试能够提供有关细胞内或全身镁状态的有用信息。

相似文献

1
Status of the mononuclear blood cell magnesium assay.单核血细胞镁含量测定的现状
J Am Coll Nutr. 1987 Apr;6(2):105-7. doi: 10.1080/07315724.1987.10720166.
2
Status of the determination of magnesium in mononuclear blood cells in humans.
Magnesium. 1988;7(5-6):300-5.
3
Mononuclear blood cell magnesium content and serum magnesium concentration in critically ill hypomagnesemic patients after replacement therapy.重症低镁血症患者补充治疗后单核血细胞镁含量及血清镁浓度
Nutrition. 1997 Apr;13(4):303-8.
4
Mononuclear cell magnesium content remains unchanged in various hypertensive disorders of pregnancy.
Gynecol Obstet Invest. 1994;38(4):220-2. doi: 10.1159/000292485.
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Blood mononuclear cell magnesium in normal pregnancy and preeclampsia.
J Am Coll Nutr. 1987 Apr;6(2):121-4. doi: 10.1080/07315724.1987.10720169.
6
Precision of the magnesium determination in mononuclear blood cells and erythrocytes.单核血细胞和红细胞中镁测定的精密度。
Clin Biochem. 1997 Apr;30(3):203-8. doi: 10.1016/s0009-9120(97)00034-9.
7
Serum and monocyte magnesium levels in two groups of patients at term.两组足月患者的血清和单核细胞镁水平。
J Am Coll Nutr. 1987 Apr;6(2):189. doi: 10.1080/07315724.1987.10720181.
8
[Magnesium content of serum in pregnancy-induced hypertension].[妊娠期高血压疾病患者血清镁含量]
Gynakol Geburtshilfliche Rundsch. 1993;33(2):92-3. doi: 10.1159/000272075.
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Magnesium content and concentration of mononuclear and T lymphocyte blood cells.单核细胞和T淋巴细胞血细胞中的镁含量及浓度。
Magnesium. 1988;7(4):219-24.
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Serum and intracellular magnesium during normal pregnancy and in patients with pre-eclampsia.
Br J Obstet Gynaecol. 1992 Mar;99(3):207-11. doi: 10.1111/j.1471-0528.1992.tb14500.x.

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