辉瑞-生物科技 COVID-19 疫苗接种后出现的抗中性粒细胞胞浆抗体相关性血管炎。
ANCA-Associated Vasculitis following the First Dose of Pfizer-BioNTech COVID-19 Vaccine.
机构信息
Department of Internal Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut, USA,
Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
出版信息
Nephron. 2023;147(2):103-107. doi: 10.1159/000525562. Epub 2022 Jul 18.
Abstract
Coronavirus disease (COVID-19) vaccine can alter the body's immunological balance leading to autoimmune disease in rare cases. Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is one of the autoimmune diseases which have been rarely reported to appear post-COVID-19 vaccine. Herein, we report the case of a 47-year-old woman who developed acute renal failure few days after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine. Corticosteroids along with azathioprine were used for the management.
摘要
新型冠状病毒疾病（COVID-19）疫苗可改变机体的免疫平衡，导致罕见情况下发生自身免疫性疾病。抗中性粒细胞胞质抗体（ANCA）相关性血管炎是一种自身免疫性疾病，有少数报道称其在接种 COVID-19 疫苗后出现。在此，我们报告了一例 47 岁女性，在接种辉瑞-生物科技公司的第一剂 COVID-19 疫苗后几天出现急性肾衰竭。使用皮质类固醇和硫唑嘌呤进行治疗。
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