Liyang Center for Disease Control and Prevention, Liyang Health Bureau, Liyang, China.
Department of Epidemiology and Biostatistics, Soochow University Medical College, Suzhou, China.
BMJ Open. 2022 Jul 18;12(7):e060978. doi: 10.1136/bmjopen-2022-060978.
The Liyang cohort study on chronic diseases and risk factors monitoring in China (Liyang Study) is a prospective population-based study which aims to investigate and identify the determinants of the most prevalent chronic non-communicable diseases (NCDs) and to evaluate the impact of demographic characteristics, lifestyle, dietary habits, cognition, disability and NCDs on the health-related quality of life.
Between March 2019 and June 2020, 10 056 individuals aged ≥18 years were administered a baseline survey through a multistage cluster random sampling in Liyang City, southern Jiangsu Province, China.
The Liyang Study included detailed sociodemographic, anthropometric and health-related behaviour, common NCDs and blood sample information. Moreover, the study gathered a series of data on specific scales including the activities of daily living, instrumental activities of daily living, abbreviated mental test, Food Frequency Questionnaire and EuroQol 5-Dimensions 5-Levels Scale. Of the 10 056 participants, 52.92% (n=5322) were female and 92.26% (n=9278) came from rural areas. The mean age was 49.9±16.2 years. Men were more likely to have a higher level of education, annual income and a paid job than women (p<0.05). The top three overall most prevalent NCDs in the study were hypertension (18.06%, n=1815), digestive diseases (7.88%, n=791), and arthritis or rheumatism (5.28%, n=530). Women had a significantly higher prevalence of diabetes (5.46%, n=290 vs 4.42%, n=209, p=0.016) and arthritis (6.04%, n=321 vs 4.42%, n=209, p<0.001) than men, while the opposite was true for chronic lung diseases such as chronic obstructive pulmonary disease (1.37%, n=65 vs 0.92%, n=49, p=0.032) and chronic hepatic diseases (0.80%, n=38 vs 0.47%, n=25, p=0.035).
The current study will give valuable insights into the association between sociodemographic factors, health-related behaviour, diet, cognition, disability and genetic factors and the most prevalent NCDs among local community residents. Starting from 2022, a follow-up survey will be conducted every 3 years to further explore the causal relationship between the above factors and NCDs.
中国慢性病和危险因素监测的溧阳队列研究（溧阳研究）是一项前瞻性的基于人群的研究，旨在调查和确定最常见的慢性非传染性疾病（NCDs）的决定因素，并评估人口特征、生活方式、饮食习惯、认知、残疾和 NCDs 对健康相关生活质量的影响。
2019 年 3 月至 2020 年 6 月期间，通过在中国江苏省南部溧阳市的多阶段聚类随机抽样，对 10056 名年龄≥18 岁的个体进行了基线调查。
溧阳研究包括详细的社会人口统计学、人体测量和健康相关行为、常见的 NCDs 和血液样本信息。此外，该研究还收集了一系列特定量表的数据，包括日常生活活动、工具性日常生活活动、简短精神测试、食物频率问卷和 EuroQol 5 维度 5 水平量表。在 10056 名参与者中，52.92%（n=5322）为女性，92.26%（n=9278）来自农村地区。平均年龄为 49.9±16.2 岁。男性比女性更有可能接受更高水平的教育、年收入和有薪工作（p<0.05）。研究中最常见的三种总体 NCDs 是高血压（18.06%，n=1815）、消化系统疾病（7.88%，n=791）和关节炎或风湿病（5.28%，n=530）。女性患糖尿病（5.46%，n=290 vs 4.42%，n=209，p=0.016）和关节炎（6.04%，n=321 vs 4.42%，n=209，p<0.001）的比例明显高于男性，而慢性肺部疾病（如慢性阻塞性肺疾病（1.37%，n=65 vs 0.92%，n=49，p=0.032）和慢性肝病（0.80%，n=38 vs 0.47%，n=25，p=0.035）则相反。
目前的研究将深入了解社会人口统计学因素、健康相关行为、饮食、认知、残疾和遗传因素与当地社区居民最常见的 NCDs 之间的关联。从 2022 年开始，将每 3 年进行一次随访调查，以进一步探讨上述因素与 NCDs 之间的因果关系。
