Lenz S, Leeton J
J In Vitro Fert Embryo Transf. 1987 Feb;4(1):18-22. doi: 10.1007/BF01555430.
Ultrasonically guided transvesical puncture of the uterine endometrial cavity was carried out in 16 patients to evaluate the feasibility of embryo transfer by this procedure. Instillation of fluid into the uterine cavity was achieved in all cases and easily performed in 15 patients. In one patient the fundal endometrium was reached in the third attempt. Instillation of fluid within the endometrium was attempted unsuccessfully in four patients, as the fluid leaked into the uterine cavity. In 12 patients 2-4 ml of fluid was injected. The fluid passed down through the cervix in patients in the luteal phase (nine patients) when 3 ml or more was injected. When a smaller amount of fluid was instilled it remained inside the cavity. In one patient in the preovulatory phase the fluid was actively pumped by uterine contractions into the vagina. Two cases in the proliferative phase showed no leakage from the cervix when 1.5 and 2 ml of fluid was injected, respectively.
对16例患者进行了超声引导下经膀胱穿刺子宫子宫内膜腔，以评估通过该操作进行胚胎移植的可行性。所有病例均成功向子宫腔内注入液体，15例患者操作轻松完成。1例患者在第三次尝试时到达子宫底部内膜。4例患者向子宫内膜内注入液体未成功，因为液体漏入子宫腔。12例患者注入了2 - 4毫升液体。当注入3毫升或更多液体时，处于黄体期的患者（9例）液体通过宫颈下行。当注入较少量液体时，液体留在腔内。1例处于排卵前期的患者，液体被子宫收缩主动泵入阴道。增殖期的2例患者，分别注入1.5毫升和2毫升液体时，宫颈无渗漏。
