MD, Piraeus, Greece.
MD,PhD, Piraeus, Greece.
Folia Med (Plovdiv). 2021 Dec 31;63(6):990-993. doi: 10.3897/folmed.63.e58002.
Crohn's disease is a multi-systemic chronic inflammatory disease that can affect various organs besides the gastrointestinal tract such as joints, uvea, and the skin. Vulvar Crohn's disease is a rare entity occurring with vulvar lesions that show typical Crohn's disease granulomatous inflammation but are not contiguous with the gastrointestinal involvement. Vulvar Crohn's disease can be easily confused with other granulomatous diseases and awareness that such involvement may precede gastrointestinal symptoms must be raised. Few cases of vulvar Crohn's disease have been reported in the literature to date. Here, we report a case of a 43-year-old woman with a 6-month history of a vulvar lesion; the patient was diagnosed with Crohn's disease of the large bowel just over a year ago.
克罗恩病是一种多系统慢性炎症性疾病，除胃肠道外，还可累及关节、葡萄膜和皮肤等多个器官。外阴克罗恩病较为罕见，病变主要位于外阴，组织学上表现为典型的克罗恩病肉芽肿性炎症，但与胃肠道病变不连续。外阴克罗恩病容易与其他肉芽肿性疾病相混淆，因此，对于此类病变，即使无胃肠道症状，也应提高警惕，考虑该病的可能。目前，文献中仅报道了少数几例外阴克罗恩病病例。在此，我们报告 1 例 43 岁女性，外阴病变 6 个月，1 年多前被诊断为大肠克罗恩病。
