Shoib Sheikh, Kotra Madhulika, Javed Sana, Nguyen Vinh-Son, Malathesh Barikar C
Department of Psychiatry, Jawahar Lal Nehru Memorial Hospital, Srinagar, Kashmir, India.
M S Ramaiah Medical College, Bangalore, India.
Horm Mol Biol Clin Investig. 2022 Jul 15;43(4):505-511. doi: 10.1515/hmbci-2021-0099. eCollection 2022 Dec 1.
Esketamine, which is an S-enantiomer of ketamine, is better than conventional antidepressants and even better than R-ketamine. This article discusses the mechanism of action of Esketamine, how different it is from other antidepressants, its side effect profile, indications for use, various routes of administration and the review of existing literature on Esketamine.
艾氯胺酮是氯胺酮的S-对映体,它比传统抗抑郁药效果更好,甚至优于R-氯胺酮。本文讨论了艾氯胺酮的作用机制、与其他抗抑郁药的差异、副作用、使用指征、各种给药途径以及关于艾氯胺酮的现有文献综述。