Department of Cardiovascular Sciences and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, University of Leicester and University Hospitals of Leicester NHS Trust, Groby Road, Leicester, LE3 9QP, United Kingdom.
Department of Cardiovascular Sciences and the NIHR Leicester Biomedical Research Centre, Glenfield Hospital, University of Leicester and University Hospitals of Leicester NHS Trust, Groby Road, Leicester, LE3 9QP, United Kingdom.
Cardiol Clin. 2022 Aug;40(3):309-320. doi: 10.1016/j.ccl.2022.03.002. Epub 2022 Mar 23.
The novel SARS-CoV-2 has directly and indirectly impacted patients with acute coronary syndrome (ACS). The onset of the COVID-19 pandemic correlated with an abrupt decline in hospitalizations with ACS and increased out-of-hospital deaths. Worse outcomes in ACS patients with concomitant COVID-19 have been reported, and acute myocardial injury secondary to SARS-CoV-2 infection is recognized. A rapid adaptation of existing ACS pathways has been required such that overburdened health care systems may manage both a novel contagion and existing illness. As SARS-CoV-2 is now endemic, future research is required to better define the complex interplay of COVID-19 infection and cardiovascular disease.
新型严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)直接或间接影响了急性冠状动脉综合征(ACS)患者。COVID-19 大流行的爆发与 ACS 住院患者数量的急剧下降和院外死亡人数的增加有关。据报道,合并 COVID-19 的 ACS 患者预后更差,并且认识到 SARS-CoV-2 感染引起的急性心肌损伤。需要对现有的 ACS 途径进行快速调整,以便负担过重的医疗保健系统能够同时管理新的传染病和现有疾病。由于 SARS-CoV-2 现在已成为地方病,因此需要进行未来的研究以更好地确定 COVID-19 感染与心血管疾病的复杂相互作用。