Metaxa Cancer Hospital, Piraeus, Greece.
Folia Med (Plovdiv). 2022 Apr 30;64(2):341-347. doi: 10.3897/folmed.64.e60937.
Uterine angiolipoleiomyomas are rare, benign mixed mesenchymal lesions. A manifestation in the gynecological region is quite uncommon, with few cases described in the literature so far. We present an interesting case of a 59-year-old woman diagnosed with uterine angiolipoleiomyoma, and the results of the conducted systematic review of the literature. The patient presented with a pelvic mass masquerading as a leiomyoma on the ultrasound and postmenopausal vaginal bleeding. At laparotomy, a large uterus was noticed and the histopathology set the diagnosis of angiolipoleiomyoma. Immunohistochemistry revealed negativity for Melan-A and HMB-45 melanoma-specific antibodies and positivity for Van Gieson and orcein histochemical stains.
子宫血管平滑肌脂肪瘤是一种罕见的良性混合性间叶瘤。在妇科区域的表现相当罕见，目前文献中仅描述了少数几例。我们报告了一例 59 岁女性的子宫血管平滑肌脂肪瘤的有趣病例，并对文献进行了系统回顾。患者表现为盆腔肿块，超声检查表现为子宫肌瘤，绝经后阴道出血。剖腹探查时发现子宫增大，组织病理学诊断为血管平滑肌脂肪瘤。免疫组化显示黑色素瘤特异性抗体 Melan-A 和 HMB-45 阴性，而 Van Gieson 和奥辛固红组织化学染色阳性。
