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腓骨原发性骨肿瘤的特征及术后临床和功能结局。

Characterization of primary fibular bone tumors and post-surgical clinical and functional outcomes.

机构信息

Abdurrahman Yurtaslan Ankara Onkoloji Eğitim ve Araştırma Hastanesi, Ortopedi ve Travmatoloji Kliniği, 06200 Yenimahalle, Ankara, Türkiye.

出版信息

Jt Dis Relat Surg. 2022;33(2):419-425. doi: 10.52312/jdrs.2022.624. Epub 2022 Jul 6.

DOI:10.52312/jdrs.2022.624
PMID:35852203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9361090/
Abstract

OBJECTIVES

In this study, we present the characterization of tumors located in the fibula, which is a rare site for tumors, and the clinical and functional results of patients with fibular tumors that we operated in our clinic.

PATIENTS AND METHODS

Between February 2008 and December 2018, a total of 104 patients (58 males, 46 females; mean age: 26±18 years; range, 3 to 78 years) who were operated for tumor located in the fibula were retrospectively analyzed. Demographic data, histopathological diagnosis, tumor localization, surgical method and postoperative complications, metastases, follow-up time, and functional results of the patients were recorded. The fibula was divided into three groups as proximal, diaphysis and distal one-third.

RESULTS

The mean follow-up was 56±25.3 (range, 24 to 108) months. Eighty (76.9%), seven (6.7%) and 17 (16.3%) patients were located proximal, diaphysis and distal to the fibula, respectively. The number of patients with malignant tumors located in the fibula was 26 (25%), the tumor was benign in 54 (51.9%) patients and 24 (23%) tumors were borderline. The most common tumor localized to the fibula was osteochondroma with 28 (26.9%) patients. The most common malignant tumors located in the fibula were Ewing sarcoma and osteosarcoma in 11 patients each. The most common surgical method was curettage in 44 (42.3%) patients. Distant organ metastases were present in 18 (17.3%) patients. The Musculoskeletal Tumor Society score of 17 patients who underwent resection of the proximal fibula were 87%.

CONCLUSION

Fibula is a rare location for tumors and fibula tumors tend to be located more proximal. Tumors located in the fibula have good functional outcomes after surgery.

摘要

目的

本研究旨在对位于腓骨的肿瘤进行特征描述,腓骨是肿瘤的罕见发病部位,并报告在我院接受治疗的腓骨肿瘤患者的临床和功能结果。

方法

2008 年 2 月至 2018 年 12 月,回顾性分析了 104 例(58 例男性,46 例女性;平均年龄:26±18 岁;范围:3 至 78 岁)因腓骨肿瘤而接受手术的患者。记录患者的人口统计学数据、组织病理学诊断、肿瘤定位、手术方法和术后并发症、转移、随访时间以及患者的功能结果。将腓骨分为近侧、骨干和远 1/3 三部分。

结果

平均随访时间为 56±25.3 个月(范围:24 至 108 个月)。80 例(76.9%)、7 例(6.7%)和 17 例(16.3%)患者的肿瘤分别位于腓骨的近侧、骨干和远 1/3 。26 例(25%)患者的腓骨肿瘤为恶性,54 例(51.9%)患者的肿瘤为良性,24 例(23%)患者的肿瘤为交界性。最常见的位于腓骨的肿瘤是骨软骨瘤,有 28 例(26.9%)患者。最常见的位于腓骨的恶性肿瘤是尤文肉瘤和骨肉瘤,各有 11 例患者。44 例(42.3%)患者采用刮除术。18 例(17.3%)患者发生远处器官转移。17 例接受近端腓骨切除的患者的肌肉骨骼肿瘤协会评分(Musculoskeletal Tumor Society score)为 87%。

结论

腓骨是肿瘤的罕见发病部位,腓骨肿瘤更倾向于位于近侧。腓骨肿瘤手术后功能结果良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e22/9361090/793b3f067fba/JDRS-2022-33-2-419-425-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e22/9361090/c2f47b4e2f21/JDRS-2022-33-2-419-425-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e22/9361090/d1f9d2e66430/JDRS-2022-33-2-419-425-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e22/9361090/793b3f067fba/JDRS-2022-33-2-419-425-F3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e22/9361090/c2f47b4e2f21/JDRS-2022-33-2-419-425-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e22/9361090/d1f9d2e66430/JDRS-2022-33-2-419-425-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e22/9361090/793b3f067fba/JDRS-2022-33-2-419-425-F3.jpg

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本文引用的文献

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An Epidemiological Study of Primary Bone Tumors of the Fibula.腓骨原发性骨肿瘤的流行病学研究
Arch Bone Jt Surg. 2021 Sep;9(5):548-553. doi: 10.22038/abjs.2020.47057.2299.
2
Management and retrospective analysis of tumors and tumor-like lesions localized in the talus.距骨内肿瘤及肿瘤样病变的诊治与回顾性分析
Jt Dis Relat Surg. 2021;32(1):218-223. doi: 10.5606/ehc.2021.78769. Epub 2021 Jan 6.
3
Surgical management of primary malignant proximal fibular tumors: Functional and clinical outcomes of 23 patients.原发性近端腓骨恶性肿瘤的手术治疗:23例患者的功能和临床结果
Eklem Hastalik Cerrahisi. 2019 Apr;30(1):24-31. doi: 10.5606/ehc.2019.62888.
4
The incidence and distribution of primary fibula tumors and tumor-like lesions: A 35-year experience.原发性腓骨肿瘤及肿瘤样病变的发病率和分布:35年经验总结
J Orthop Surg (Hong Kong). 2018 May-Aug;26(3):2309499018798180. doi: 10.1177/2309499018798180.
5
Surgical management of proximal fibular tumors: risk factors for recurrence and complications.腓骨近端肿瘤的手术治疗:复发和并发症的危险因素
J Int Med Res. 2018 May;46(5):1884-1892. doi: 10.1177/0300060518762677. Epub 2018 Mar 20.
6
Fibulectomy for Primary Proximal Fibular Bone Tumors: A Functional and Clinical Outcome in 46 Patients.原发性近端腓骨骨肿瘤的腓骨切除术:46例患者的功能和临床结果
Indian J Orthop. 2018 Jan-Feb;52(1):3-9. doi: 10.4103/ortho.IJOrtho_323_16.
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Surgical management of proximal fibular tumors: A report of 12 cases.腓骨近端肿瘤的外科治疗:12例报告
J Bone Oncol. 2016 Jun 8;5(4):163-166. doi: 10.1016/j.jbo.2016.06.001. eCollection 2016 Nov.
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