Dobson G P, Hochachka P W
J Exp Biol. 1987 May;129:125-40. doi: 10.1242/jeb.129.1.125.
Measurements of metabolite concentrations before and immediately after swimming of trout to exhaustion indicate that all three potential endogenous fuels of anaerobic metabolism [glycogen, phosphocreatine (PCr) and adenosine triphosphate (ATP)] are utilized during anaerobic white muscle work. Lactate, H+, creatine Pi, NH4+ and inosine monophosphate (IMP) are formed in the process. Glycolysis is considered to be functionally (if loosely) coupled to adenylate depletion by setting up conditions favouring AMP-deaminase-catalysed formation of IMP and NH3. During recovery under these experimental conditions, glycolysis appears to outcompete oxidative metabolism as an ADP acceptor; therefore, in this kind of white muscle, glycolysis is also linked to IMP reconversion to AMP and thus to adenylate replenishment. The net process generates H+, which is why ATP replenishment must be completed before PCr concentrations can be returned to pre-exercise values.
对虹鳟鱼游至精疲力竭前后代谢物浓度的测量表明，在厌氧白肌工作期间，无氧代谢的所有三种潜在内源性燃料（糖原、磷酸肌酸（PCr）和三磷酸腺苷（ATP））都会被利用。在此过程中会形成乳酸、H⁺、肌酸磷酸、NH₄⁺和肌苷单磷酸（IMP）。糖酵解在功能上（如果关系较为松散的话）被认为是通过创造有利于AMP脱氨酶催化形成IMP和NH₃的条件来与腺苷酸消耗相耦合。在这些实验条件下的恢复过程中，糖酵解似乎比氧化代谢更具竞争力，可作为ADP的受体；因此，在这种白肌中，糖酵解也与IMP再转化为AMP以及腺苷酸补充相关联。该净过程会产生H⁺，这就是为什么必须在PCr浓度恢复到运动前值之前完成ATP补充的原因。
