Suppr超能文献

青少年特发性脊柱侧凸的支具治疗:从支具治疗到骨骼成熟的回顾性研究。

Bracing for juvenile idiopathic scoliosis: retrospective review from bracing to skeletal maturity.

机构信息

Department of Orthopaedic Surgery, Shriners Hospital for Children Northern California, 2425 Stockton Blvd, Sacramento, CA, 95817, USA.

Department of Orthopaedic Surgery, University of California Davis, 4680 Y St, Sacramento, CA, 95817, USA.

出版信息

Spine Deform. 2022 Nov;10(6):1349-1358. doi: 10.1007/s43390-022-00544-2. Epub 2022 Jul 19.

Abstract

BACKGROUND

Juvenile idiopathic scoliosis (JIS) outcomes with brace treatment are limited with poorly described bracing protocols. Between 49 and 100% of children with JIS will progress to surgery, however, young age, long follow-up, and varying treatment methods make studying this population difficult. The purpose of this study is to report the outcomes of bracing in JIS treated with a Boston brace™ and identify risk factors for progression and surgical intervention.

METHODS

This is a single-center retrospective review of 175 patients with JIS who initiated brace treatment between the age of 4 and 9 years. A cohort of 140 children reached skeletal maturity; 91 children had surgery or at least 2 year follow-up after brace completion. Standard in-brace protocol for scoliosis 20° was a Boston brace for 18-20 h/day after MRI (n = 82). Family history, MRI abnormalities, comorbidities, curve type, curve magnitude, bracing duration, number of braces, compliance by report, and surgical interventions were recorded.

RESULTS

Children were average 7.9 years old (range 4.1-9.8) at the initiation of bracing. The Boston brace™ was prescribed in 82 patients and nine used night bending brace. Mid-thoracic curves (53%) was the most frequent deformity. Maximum curve at presentation was on average 30 ± 9 degrees, in-brace curve angle was 16 ± 8 degrees, and in-brace correction was 58 ± 24 percent. Patients were braced an average of 4.6 ± 1.9 years. 61/91 (67%) went on to posterior spinal fusion at 13.3 ± 2.1 (range 9.3-20.9) years and curve magnitude of 61 ± 12 degrees. Of those that underwent surgery, 49/55 (86%) progressed > 10°, 6/55 (11%) stabilized within 10°, and 0/55 (0%) improved > 10° with brace wear. No children underwent growth-friendly posterior instrumentation. Of the 28 who did not have surgical correction, 3 (11%) progressed > 10°, 13/28 (46%) stabilized within 10°, and 12/28 (43%) improved > 10° with brace wear.

CONCLUSIONS

This large series of JIS patients with bracing followed to skeletal maturity with long-term follow-up. Surgery was avoided in 33% of children with minimal to no progression, and no child underwent posterior growth-friendly constructs. Risk factors of needing surgery were noncompliance and larger curves at presentation.

摘要

背景

支具治疗青少年特发性脊柱侧凸(JIS)的效果有限,且支具治疗方案描述不佳。约有 49%至 100%的 JIS 患儿需要接受手术治疗,然而,患儿年龄小、随访时间长以及治疗方法多样等因素使得研究这一人群变得困难。本研究旨在报告使用 Boston 支具治疗 JIS 的支具治疗结果,并确定进展和手术干预的风险因素。

方法

这是一项单中心回顾性研究,纳入了 175 例 4 至 9 岁开始支具治疗的 JIS 患儿。其中 140 例患儿达到骨骼成熟度;91 例患儿完成支具治疗后接受了手术或至少 2 年的随访。MRI 检查后,支具治疗标准为 Cobb 角 20°的脊柱侧凸患儿,支具治疗方案为 Boston 支具,每日佩戴 18-20 小时(n=82)。记录家族史、MRI 异常、合并症、脊柱侧凸类型、侧凸程度、支具治疗时间、支具使用数量、支具佩戴依从性和手术干预情况。

结果

患儿开始支具治疗时的平均年龄为 7.9 岁(范围为 4.1-9.8 岁)。82 例患儿使用了 Boston 支具,9 例患儿使用了夜间弯曲支具。最常见的畸形是胸中段脊柱侧凸(53%)。初始时的最大侧凸角度平均为 30°±9°,支具内矫正角度为 16°±8°,支具矫正率为 58%±24%。患儿平均佩戴支具 4.6±1.9 年。91 例患儿中有 61 例(67%)在 13.3±2.1 岁(范围为 9.3-20.9 岁)时接受了后路脊柱融合术,侧凸角度为 61°±12°。在接受手术治疗的患儿中,49/55(86%)的患儿术后侧凸进展超过 10°,6/55(11%)的患儿术后侧凸稳定在 10°以内,0/55(0%)的患儿术后侧凸改善超过 10°。没有患儿接受了生长型后路内固定治疗。在未接受手术矫正的 28 例患儿中,3 例(11%)术后侧凸进展超过 10°,13/28(46%)术后侧凸稳定在 10°以内,12/28(43%)术后侧凸改善超过 10°。

结论

本研究对 175 例 JIS 患儿进行了支具治疗,并进行了长期随访至骨骼成熟。33%的患儿无需手术治疗,其脊柱侧凸进展轻微或无进展,且无患儿接受了生长型后路内固定治疗。需要手术治疗的风险因素是不依从支具治疗和初始时的侧凸角度较大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/509e/9579105/0a9422acbc64/43390_2022_544_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验