School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.
BMC Health Serv Res. 2022 Jul 19;22(1):926. doi: 10.1186/s12913-022-08330-6.
Generic substitution is a good approach to reduce pharmaceutical expenses without compromising healthcare quality. Yet, the practice of generic substitution has been contentious due to concerns on quality and efficacy.
This study was aimed to assess knowledge, attitude and practice among pharmacy professionals toward generic substitution in community drug retail outlets in Jimma town, Southwest Ethiopia.
A descriptive cross-sectional study was conducted among pharmacy professionals working in community drug retail outlets. Data was collected using a self-administered questionnaire. Knowledge was tested using a 3-point response format consisting of "Yes," "No" and "I am not sure." Attitude was evaluated using the 5-point Likert scale ranging from 1(strong agreement) to 5 (strong disagreement). The practice was examined as never, seldom, sometimes, often, and always with scores ranging from 0 to 4. The influences of socio-demographic factors on knowledge, attitude, and practice were tested using the Mann-Whitney U and Kruskal-Wallis tests as appropriate. P ≤ 0.05 was considered statistically significant.
The mean knowledge score of participants regarding generic medicines was 5.75 ± 1.79. Only 32 respondents (30.2%) of the participants were knowledgeable about the generic substitution. 54 (50.9%) of respondents had positive attitude toward generic substitution and 52 (49.1%) had practiced generic substitution. The year of experience had a significant effect on knowledge (X = 9.14, p = 0.01) and practice (X = 4.71, p = 0.03) of generic substitution.
Our study found that pharmacy professionals working in community drug retail outlets in Jimma town had lack of knowledge about generic substitution. Conversely, an enormous amount of participants had positive attitude toward generic substitution and nearly half of them had practiced generic substitution. The year of experience had a significant effect on knowledge and practice of generic substitution.
用仿制药替代是降低药品费用而不影响医疗质量的好方法。然而,由于对质量和疗效的担忧,仿制药替代的做法一直存在争议。
本研究旨在评估埃塞俄比亚西南部 Jimma 镇社区药品零售店药剂师对仿制药替代的知识、态度和实践。
这是一项在社区药品零售店工作的药剂师中进行的描述性横断面研究。使用自填式问卷收集数据。知识通过 3 分制回答(“是”、“否”和“不确定”)进行测试。态度使用 5 分李克特量表评估,范围从 1(完全同意)到 5(完全不同意)。实践情况通过从未、很少、有时、经常和总是进行检查,得分范围从 0 到 4。使用 Mann-Whitney U 和 Kruskal-Wallis 检验(视情况而定)检验社会人口统计学因素对知识、态度和实践的影响。P ≤ 0.05 被认为具有统计学意义。
参与者对仿制药的平均知识得分是 5.75±1.79。只有 32 名(30.2%)参与者对仿制药替代有一定了解。54 名(50.9%)受访者对仿制药替代持积极态度,52 名(49.1%)有过仿制药替代实践。工作年限对知识(X=9.14,p=0.01)和仿制药替代实践(X=4.71,p=0.03)有显著影响。
我们的研究发现,Jimma 镇社区药品零售店的药剂师对仿制药替代缺乏了解。相反,绝大多数参与者对仿制药替代持积极态度,近一半的人有过仿制药替代实践。工作年限对仿制药替代的知识和实践有显著影响。