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评估沙特阿拉伯社区药剂师对通用名药物替代的看法和做法:一项横断面研究。

Evaluating community pharmacists' perspectives and practices concerning generic medicines substitution in Saudi Arabia: A cross-sectional study.

作者信息

Alkhuzaee Fahad S, Almalki Hamdan M, Attar Ammar Y, Althubiani Shoeab I, Almuallim Wassam Ali, Cheema Ejaz, Hadi Muhammad Abdul

机构信息

Department of Clinical Pharmacy, Umm-Al-Qura University, Makkah, Saudi Arabia.

Department of Clinical Pharmacy, Umm-Al-Qura University, Makkah, Saudi Arabia; School of Healthcare, University of Leeds, Leeds, United Kingdom.

出版信息

Health Policy. 2016 Dec;120(12):1412-1419. doi: 10.1016/j.healthpol.2016.09.018. Epub 2016 Oct 11.

Abstract

OBJECTIVES

To assess the community pharmacists' knowledge, attitude, perception and current practices towards generic medicines substitution in Saudi Arabia.

METHODS

A cross-sectional study was conducted between February and March 2016 in the Makkah region, Saudi Arabia. A 25-item, structured, validated, pilot-tested and self-completed questionnaire was used to achieve study objectives. A 4-step systematic sampling technique was used to recruit community pharmacists. Data were analysed using SPSS version 20.

RESULTS

Of 128 community pharmacists approached, 121 participated in the study (response rate=95%). Majority of the participants (n=108; 89.3%) had graduated from Egypt, were working as staff pharmacists (n=85; 70%) and had BPharm degree (97; 80.2%). Only 26 (22%) of the participants correctly answered all knowledge questions accurately. No statistically significant difference in total knowledge score was observed across different sociodemographic characteristics of participants (all P>0.05).Two-thirds of the respondents (83; 68.2%) supported the use of generic substitution. Medicines cost and patients' request were the most commonly cited reasons for performing generic substitution. Country of graduation (P=0.01) and number of years of practicing in Saudi Arabia (P=0.02) was associated with the pharmacists' support towards generic substitution.

CONCLUSION

The community pharmacists had clear knowledge deficits about generic medicines and their substitution which may partly explain low consumption of generic medicines in Saudi Arabia. Healthcare policy makers need to improve awareness about the safety and efficacy of generic medicines and promote their use in order to cut down cost of medicines and overall healthcare expenditure.

摘要

目的

评估沙特阿拉伯社区药剂师对通用名药物替代的知识、态度、认知及当前做法。

方法

2016年2月至3月在沙特阿拉伯麦加地区进行了一项横断面研究。采用一份包含25个条目的结构化、经过验证、预试验且可自行完成的问卷来实现研究目标。使用四步系统抽样技术招募社区药剂师。数据采用SPSS 20版进行分析。

结果

在接触的128名社区药剂师中,121名参与了研究(应答率=95%)。大多数参与者(n=108;89.3%)毕业于埃及,担任药剂师(n=85;70%),拥有药学学士学位(97;80.2%)。只有26名(22%)参与者准确正确回答了所有知识问题。在参与者的不同社会人口学特征中,未观察到总知识得分有统计学显著差异(所有P>0.05)。三分之二的受访者(83;68.2%)支持使用通用名替代。药品成本和患者要求是进行通用名替代最常提及的原因。毕业国家(P=0.01)和在沙特阿拉伯的执业年限(P=0.02)与药剂师对通用名替代的支持有关。

结论

社区药剂师对通用名药物及其替代存在明显的知识缺陷,这可能部分解释了沙特阿拉伯通用名药物消费量较低的原因。医疗保健政策制定者需要提高对通用名药物安全性和有效性的认识,并推广其使用,以降低药品成本和总体医疗保健支出。

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