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隐匿性垂体病变:血色素沉着症——垂体功能障碍的一个鲜为人知的病因

The Dark Pituitary: Hemochromatosis as a Lesser-Known Cause of Pituitary Dysfunction.

作者信息

Verberckmoes Bert, Dekeyzer Sven, Decaestecker Karen

机构信息

University Hospital Ghent, BE.

出版信息

J Belg Soc Radiol. 2022 Jun 29;106(1):63. doi: 10.5334/jbsr.2771. eCollection 2022.

DOI:10.5334/jbsr.2771
PMID:35854824
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9248988/
Abstract

Iron deposition in the pituitary gland in patients with primary and secondary hemochromatosis is a lesser-known cause of pituitary dysfunction and results in T2- and T2*-signal loss on MRI, other brain structures, in which iron deposition can be seen, are the choroid plexus and sporadically the circumventricular organs (e.g., the pineal gland).

摘要

原发性和继发性血色素沉着症患者垂体中的铁沉积是垂体功能障碍鲜为人知的原因,在MRI上表现为T2和T2*信号缺失。其他可见铁沉积的脑结构是脉络丛,偶尔还有室周器官(如松果体)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/9248988/f09a937389fb/jbsr-106-1-2771-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/9248988/8f36838a120f/jbsr-106-1-2771-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/9248988/950bfc77fca5/jbsr-106-1-2771-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/9248988/f09a937389fb/jbsr-106-1-2771-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/9248988/8f36838a120f/jbsr-106-1-2771-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/9248988/950bfc77fca5/jbsr-106-1-2771-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/9248988/f09a937389fb/jbsr-106-1-2771-g3.jpg

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J Belg Soc Radiol. 2022 Jun 29;106(1):63. doi: 10.5334/jbsr.2771. eCollection 2022.
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引用本文的文献

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Choroid plexus and pituitary gland hemochromatosis induced by transfusional iron overload: Two case reports.输血性铁过载所致脉络丛和垂体血色素沉着症:两例报告
Radiol Case Rep. 2024 Feb 13;19(5):1666-1670. doi: 10.1016/j.radcr.2024.01.059. eCollection 2024 May.
2
Iron Load Toxicity in Medicine: From Molecular and Cellular Aspects to Clinical Implications.医学中的铁负荷毒性:从分子和细胞角度到临床意义。
Int J Mol Sci. 2023 Aug 18;24(16):12928. doi: 10.3390/ijms241612928.

本文引用的文献

1
Case 179: Hereditary hemochromatosis.病例179:遗传性血色素沉着症。
Radiology. 2012 Mar;262(3):1037-41. doi: 10.1148/radiol.11102324.