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无功能垂体腺瘤切除术后患者的乳头型颅咽管瘤:病例说明

Papillary craniopharyngioma in a patient following resection of nonfunctioning pituitary adenoma: illustrative case.

作者信息

Park David J, Mishra Akash, Golub Danielle, Li Jian Y, Black Karen S, Schulder Michael

机构信息

Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York; and.

Departments of Neurosurgery.

出版信息

J Neurosurg Case Lessons. 2021 Jan 11;1(2):CASE2063. doi: 10.3171/CASE2063.

Abstract

BACKGROUND

Although craniopharyngioma and pituitary adenoma are common tumors of the sellar or suprasellar region, the development of papillary craniopharyngioma in the same sellar region after resection of a nonfunctioning pituitary adenoma has not been reported.

OBSERVATIONS

Here the authors report the first case of craniopharyngioma that developed long after resection of a pituitary adenoma. A 66-year-old male patient underwent endoscopic transsphenoidal resection for a large sellar mass, which histopathologically confirmed the diagnosis of a pituitary adenoma. He had an excellent recovery after surgery. For several years, he had no clinical or imaging evidence of tumor recurrence and then was lost to follow-up. Seven years after the initial surgery, the patient returned with a one-month history of visual field defects, and imaging confirmed a heterogeneous, cystic suprasellar mass. Endoscopic transsphenoidal resection of the tumor was performed, and histological examination showed it to be a papillary craniopharyngioma.

LESSONS

Neurosurgeons should be aware that after pituitary adenoma resection, a recurrent mass could be a craniopharyngioma, with implications for very different management recommendations.

摘要

背景

尽管颅咽管瘤和垂体腺瘤是鞍区或鞍上区的常见肿瘤,但无功能垂体腺瘤切除术后同一鞍区发生乳头状颅咽管瘤的情况尚未见报道。

观察结果

本文作者报告了首例垂体腺瘤切除术后多年发生颅咽管瘤的病例。一名66岁男性患者因鞍区巨大肿块接受了内镜经蝶窦切除术,组织病理学检查确诊为垂体腺瘤。术后恢复良好。数年来,他没有肿瘤复发的临床或影像学证据,随后失访。初次手术后7年,患者因有1个月视野缺损病史复诊,影像学检查证实鞍上有一异质性囊性肿块。对该肿瘤进行了内镜经蝶窦切除术,组织学检查显示为乳头状颅咽管瘤。

经验教训

神经外科医生应意识到,垂体腺瘤切除术后复发的肿块可能是颅咽管瘤,这对治疗建议有很大不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9bd3/9241323/62beb46a1bdc/CASE2063f1.jpg

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