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评价莫桑比克马普托市 2017-2018 年期间的耐多药结核病监测系统。

Evaluation of the multidrug-resistant tuberculosis surveillance system in Maputo City, Mozambique in the period 2017-2018.

机构信息

Field Epidemiology Training Program, Maputo, Mozambique.

National Tuberculosis Control Program, Maputo, Mozambique.

出版信息

Pan Afr Med J. 2022 Apr 7;41:284. doi: 10.11604/pamj.2022.41.284.30611. eCollection 2022.

DOI:10.11604/pamj.2022.41.284.30611
PMID:35855038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9250665/
Abstract

INTRODUCTION

multidrug-resistant tuberculosis (MDR-TB) remains a public health problem worldwide. In Mozambique, cases of MDR-TB have increased annually. In 2018, 1,206 cases were reported, as compared to 943 cases in 2017. The aim of this study was to assess the surveillance system for multidrug-resistant tuberculosis in Maputo City.

METHODS

an extract from the national database was considered for a cut-out of the City of Maputo in the period 2017-2018; the study was conducted per the guidelines of the Centers for Disease Control and Prevention, where the description of the system was carried out, and evaluation of the attributes. Each attribute was evaluated according to the established criteria and parameters.

RESULTS

the surveillance system is based on the collection of data in health centers. Four hundred and six cases of MDR-TB were notified, of which 56.8% (231/406) were male and 95.9% (386/406) were ≥15 years. The system was complex with 4 levels of information transmission. With regard to flexibility, there was no changing the variables in the database. Acceptability was good. The quality of the data was regular with discrepancy of data of 14.5%. The system was considered stable as there was no system interruption. Timeliness with case notification monthly. The system sensitivity was 72.9%, the positive predictive value (PPV) was 2.3% and regarding utility the system has fulfilled its objectives.

CONCLUSION

the system was not flexible, the data quality was regular, had moderate sensitivity and low positive predictive value. Continuous assessment of data and scale up the diagnosis for the detection of cases of MDR-TB is recommended.

摘要

简介

耐多药结核病(MDR-TB)仍然是全球公共卫生问题。在莫桑比克,MDR-TB 病例每年都在增加。2018 年报告了 1206 例,而 2017 年为 943 例。本研究旨在评估马普托市耐多药结核病监测系统。

方法

从国家数据库中提取一个 2017-2018 年马普托市的数据集;该研究是根据疾病控制和预防中心的指南进行的,对系统进行了描述和评估。根据既定标准和参数对每个属性进行评估。

结果

监测系统基于在卫生中心收集数据。共报告了 406 例耐多药结核病病例,其中 56.8%(231/406)为男性,95.9%(386/406)年龄≥15 岁。该系统具有 4 级信息传输,结构复杂。在灵活性方面,数据库中无法更改变量。可接受性良好。数据质量正常,数据差异为 14.5%。由于没有系统中断,因此该系统被认为是稳定的。每月进行病例通报,具有及时性。系统灵敏度为 72.9%,阳性预测值(PPV)为 2.3%,系统具有实用性。

结论

该系统缺乏灵活性,数据质量正常,敏感性中等,阳性预测值较低。建议持续评估数据并扩大诊断范围,以发现耐多药结核病病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2efa/9250665/c7909f6da67a/PAMJ-41-284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2efa/9250665/c7909f6da67a/PAMJ-41-284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2efa/9250665/c7909f6da67a/PAMJ-41-284-g001.jpg

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