Department of Nephrology, la Rabta Hospital, Jabbari, 1007, Tunis, Tunisia.
Research Laboratory in Renal Pathology LR00SP01, Medicine School of Tunis, Tunis El Manar University, Tunis, Tunisia.
Pan Afr Med J. 2022 Apr 14;41:305. doi: 10.11604/pamj.2022.41.305.31067. eCollection 2022.
hospital readmission after kidney transplantation is an important metric for health care quality, which associated with increased morbidity, costs and transition-of-care errors. It is influenced by population demographics and the comprehensiveness of the healthcare system. The aim of this study was to evaluate incidence causes and risk factors associated with hospital readmission within the first year after transplantation.
all patients undergoing kidney transplantation at a single center over a ten-year period were analyzed via retrospective chart review. A multivariable logistic regression analysis was performed to identify associated factors.
in 86 patients, the incidence of unplanned readmissions within the first year was 68.6% (n = 59). The main reasons for HR were infection (33%), renal events (32%), surgical complications (16%), and metabolic disturbances (9%). In univariate analyses, hospital readmission was associated with Dyslipidemia p=0.04; OR=2.6; 95% CI= [1.93-13.17], anemia p=0.011; OR=4.5; 95% CI = [1.33-15.6], hemodialysis p=0,012; OR=4.8 ; 95% CI= [1.3-18.5], new onset diabetes after transplantation p=0.05 ; OR=3.5 ; 95% CI= [1.6-13,80], medical history of cardiomyopathy p=0,016 ; OR=6.4 ; 95% CI = [5.4-7.5]. While independent risk factors were: hemodialysis vintage and cardiomyopathy. There was no difference in one-year patient survival and death-censored graft survival in HR group and non-HR group.
hospital readmissions severely affect a patient's physical and mental well-being after kidney transplantation, which is also independently associated with morbidity. Our study showed that risk factors associated with hospital readmission often reflect pretransplant comorbidity.
肾移植后住院是医疗质量的重要指标,与发病率、成本和医疗过渡期错误增加有关。它受人口统计学和医疗保健系统的全面性影响。本研究旨在评估肾移植后一年内住院的发病率、原因和相关危险因素。
通过回顾性病历分析,对在单中心接受肾移植的 86 名患者进行分析。采用多变量逻辑回归分析确定相关因素。
在 86 名患者中,一年内计划外再入院的发生率为 68.6%(n=59)。主要再入院原因是感染(33%)、肾脏事件(32%)、手术并发症(16%)和代谢紊乱(9%)。单因素分析显示,血脂异常(p=0.04);OR=2.6;95%CI=[1.93-13.17]、贫血(p=0.011);OR=4.5;95%CI=[1.33-15.6]、血液透析(p=0.012);OR=4.8;95%CI=[1.3-18.5]、移植后新发糖尿病(p=0.05);OR=3.5;95%CI=[1.6-13,80]、心肌病病史(p=0.016);OR=6.4;95%CI=[5.4-7.5]与住院有关。独立危险因素是血液透析的年限和心肌病。在再入院组和非再入院组,一年患者生存率和死亡相关移植物存活率无差异。
肾移植后住院严重影响患者的身心健康,与发病率独立相关。我们的研究表明,与住院相关的危险因素通常反映了移植前的合并症。