Porwal Mokshal H, Anderson Danyon J, Hussain Omar, Laing Brandon Robert Winston, Soliman Hesham
Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, United States.
Surg Neurol Int. 2022 Jun 17;13:256. doi: 10.25259/SNI_457_2022. eCollection 2022.
Tuberculous (TB) osteomyelitis is a rare, but challenging infection, that mandates antituberculosis antibiotics, and potentially surgical intervention. Per the Gulhane Askeri Tip Akademisi (GATA) classification system, corrective reconstruction is indicated in severe cases, where the kyphotic deformity is >20° (GATA Class III). Here, we describe a case of BCG vaccine-induced lumbar TB osteomyelitis at the L1-2 level in a patient presenting with mechanical pain and a focal, nonfixed kyphotic deformity of 36.1°. Surgery consisted of percutaneous fixation with pedicle screws without debridement, fusion arthrodesis, or anterior reconstruction.
A 77-year-old male presented with L1-2 TB osteomyelitis secondary to intravesical BCG application. A 36.1° focal nonfixed kyphotic deformity was evident on standing X-rays that reduced in the supine position. He underwent posterior percutaneous screw fixation with rods extending from the T12 to L3 levels, with resolution of his mechanical pain. Nine months later, the CT demonstrated reconstitution of the vertebral bodies (i.e., volume increase of 6.99 cm (21%) and 7.49 cm (27%) at L1 and L2, respectively). Standing X-rays after hardware removal demonstrated 32.7° of lumbar lordosis and a reduction of focal kyphosis to 12.9°.
Here, we present an exceedingly rare case of BCG vaccine-induced L1-2 spinal tuberculosis with extensive vertebral body destruction and deformity. This was effectively treated with standalone temporary pedicle fixation instead of corpectomy and reconstruction.
结核性骨髓炎是一种罕见但具有挑战性的感染性疾病,需要使用抗结核抗生素治疗,可能还需要手术干预。根据古勒汗军事医学科学院(GATA)分类系统,在严重病例中,即后凸畸形>20°(GATA III级)时,需要进行矫正重建。在此,我们描述一例卡介苗疫苗诱导的L1-2节段腰椎结核性骨髓炎病例,患者表现为机械性疼痛和36.1°的局灶性、非固定性后凸畸形。手术包括经皮椎弓根螺钉固定,无需清创、融合关节固定术或前路重建。
一名77岁男性因膀胱内应用卡介苗继发L1-2节段结核性骨髓炎。站立位X线片显示明显的36.1°局灶性非固定性后凸畸形,仰卧位时畸形减轻。他接受了从T12至L3节段的后路经皮螺钉固定及棒植入,机械性疼痛得到缓解。9个月后,CT显示椎体重建(即L1和L2椎体体积分别增加6.99 cm(21%)和7.49 cm(27%))。取出内固定后的站立位X线片显示腰椎前凸为32.7°,局灶性后凸畸形减轻至12.9°。
在此,我们报告一例极为罕见的卡介苗疫苗诱导的L1-2节段脊柱结核病例,伴有广泛的椎体破坏和畸形。采用单纯临时椎弓根固定而非椎体切除和重建有效地治疗了该病例。