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沙特阿拉伯南部地区使用超声成像技术观察减肥手术后胆囊结石形成的发生率

Incidence of Gallbladder Stone Formation After Bariatric Surgery Using Ultrasound Imaging in the Southern Region of Saudi Arabia.

作者信息

Shubayr Nasser, Elbashir Meaad, Alashban Yazeed, Ali Sarra, Jafaari Marwan, Hendi Ali, Majrashi Naif, Alyami Ali, Alumairi Nada

机构信息

Department of Diagnostic Radiology, Jazan University, Jazan, SAU.

Department of Epidemiology and Public Health, Jazan University, Jazan, SAU.

出版信息

Cureus. 2022 Jun 15;14(6):e25948. doi: 10.7759/cureus.25948. eCollection 2022 Jun.

Abstract

Background Bariatric surgery is performed for accomplishing weight loss, which can save patients from diseases associated with morbid obesity. However, rapid weight loss is one of the most important risk factors contributing to the formation of gallbladder stones. The aim of this study is to investigate the prevalence of gallstone formation among patients in the southern region of Saudi Arabia who underwent bariatric surgery and to evaluate the association between several parameters and gallstone development in these patients. Methods A retrospective study was conducted including 57 patients who did not have gallstones in the preoperative abdominal ultrasound examinations. Demographic data, such as age and gender, were obtained along with other parameters like weight loss after surgery, and time elapsed between the surgery to post-surgery US examination. The findings of the US examinations were collected and analyzed. Data were analyzed to obtain descriptive and inferential statistics. A correlation matrix to investigate the dependence between variables was conducted. Results Patients in this study underwent either sleeve gastrectomy (87.7% [n = 50]) or gastric banding procedures (12.3% [n = 7]). The occurrence of cholecystectomy was 46% after sleeve gastrectomy and 71.1% after gastric band procedures. The majority of the patients (57.9%) lost weight after surgery in the range of 20 to 40 kg. The time elapses between the surgery to post-surgery ultrasonography examination varied among patients, where less than one year, one to three years, and three to six years accounted for 47.4%, 43.9%, and 8.8%, respectively. Gallstone formation after the surgery was found in 35 (61.4%) of the total cases. Among patients who developed gallbladder stones after bariatric surgery, 62.9%, 28.4%, and 8.6% were within less than one year, one to three years, and three to six years, respectively. The results suggest a statistically significant correlation betweengallstone formation and​​​ the time elapsed after the surgery (P = 0.008) and the type of bariatric surgery (P = 0.006). Conclusion The current study found that the overall incidence rate of gallbladder stones after bariatric surgery is 61.4%. The study assumed a possible higher incidence of gallbladder stones following bariatric surgery among the population in the southern region of Saudi Arabia compared to incidence rates reported in the literature. The type of bariatric surgery and the time elapsed after the surgery were found to be of value in predicting the formation of gallstones.

摘要

背景

减肥手术旨在实现体重减轻,从而使患者免受与病态肥胖相关的疾病困扰。然而,快速体重减轻是导致胆囊结石形成的最重要风险因素之一。本研究的目的是调查沙特阿拉伯南部地区接受减肥手术患者的胆囊结石形成患病率,并评估这些患者的几个参数与胆囊结石发展之间的关联。

方法

进行了一项回顾性研究,纳入57例术前腹部超声检查未发现胆囊结石的患者。收集了年龄、性别等人口统计学数据以及其他参数,如术后体重减轻情况,以及手术至术后超声检查的时间间隔。收集并分析了超声检查结果。对数据进行分析以获得描述性和推断性统计数据。进行了相关矩阵分析以研究变量之间的依赖性。

结果

本研究中的患者接受了袖状胃切除术(87.7% [n = 50])或胃束带手术(12.3% [n = 7])。袖状胃切除术后胆囊切除术的发生率为46%,胃束带手术后为71.1%。大多数患者(57.9%)术后体重减轻20至40千克。手术至术后超声检查的时间间隔因患者而异,其中不到一年、一至三年和三至六年分别占47.4%、43.9%和8.8%。在所有病例中,术后发现35例(61.4%)形成了胆囊结石。在减肥手术后发生胆囊结石的患者中,分别有62.9%、28.4%和8.6%在不到一年、一至三年和三至六年内出现结石。结果表明,胆囊结石形成与手术后经过的时间(P = 0.008)和减肥手术类型(P = 0.006)之间存在统计学上的显著相关性。

结论

当前研究发现,减肥手术后胆囊结石的总体发生率为61.4%。该研究认为,与文献报道的发生率相比,沙特阿拉伯南部地区人群减肥手术后胆囊结石的发生率可能更高。减肥手术类型和手术后经过的时间被发现对预测胆囊结石的形成有价值。

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