Universidade Estadual de Ciências da Saúde Alagoas (UNCISAL), Maceió, AL, Brazil.
Universidade de São Paulo (USP), São Paulo, SP, Brazil.
PLoS One. 2022 Jul 20;17(7):e0271328. doi: 10.1371/journal.pone.0271328. eCollection 2022.
The socio-demographic profile of pregnant women in low- and middle- income countries is characterized by low educational attainment and unemployment, leading to social and economic morbidity. characterized by limited opportunities for education, employment, and marriage, which are strongly related to the stigmatization of the disease. The study of the socio- profile and obstetric outcomes of pregnant women with epilepsy in Alagoas, Brazil, may help understand this scenario and facilitate the development of public policy strategies to reduce local morbidity.
We aimed to describe the sociodemographic profile of pregnant women with epilepsy and obstetric outcomes in Alagoas, Brazil.
This cohort study was based on medical records of pregnant women with epilepsy in Brazilian high-risk maternity hospitals from 2008 to 2020. The following data were collected: age, race, education, marital status, occupation, number of pregnancies, delivery, and abortion. The inclusion criteria were pregnant women with and without epilepsy (control group) aged < 40 years.
The prevalence of PWWE was 0.49% (n = 224/44,917). Cesarean delivery was more frequent in PWWE than in pregnant women without epilepsy (adjusted odds ratio [OR] = 22.0; 95% confidence interval [CI] = 14.35-33.73; p<0,01). Abortion was associated with PWWE (OR adjusted = 1.72; 95% CI = 1.13-2.61; p = 0.01). Pregnant women in the countryside were more likely to develop epilepsy than those born in the capital (OR = 1.55; 95% CI = 1.12-2.14; p <0.01).
The PWWE socio-demographic profile of the Alagoas had a predominance of brown- colored skin, single status, homemakers, and illiteracy with a high proportion residing in the interior of the state. The obstetrics data show a higher incidence of cesarean deliveries and miscarriages.
中低收入国家孕妇的社会人口学特征表现为受教育程度低和失业，导致社会和经济病态。这些特征受到疾病污名化的限制，导致教育、就业和婚姻机会有限。对巴西阿拉戈斯州患有癫痫症的孕妇的社会人口学特征和产科结局进行研究，可能有助于了解这种情况，并促进制定减少当地发病率的公共政策策略。
我们旨在描述巴西阿拉戈斯州患有癫痫症的孕妇的社会人口学特征和产科结局。
本队列研究基于 2008 年至 2020 年巴西高危产妇医院中患有癫痫症的孕妇的医疗记录。收集了以下数据：年龄、种族、教育程度、婚姻状况、职业、妊娠次数、分娩和流产。纳入标准为年龄<40 岁的患有癫痫症和无癫痫症的孕妇（对照组）。
患有癫痫症的孕妇（PWWE）的患病率为 0.49%（n=224/44,917）。PWWE 组的剖宫产率高于无癫痫症的孕妇（调整后的优势比[OR] = 22.0；95%置信区间[CI] = 14.35-33.73；p<0.01）。PWWE 与流产相关（调整后的 OR = 1.72；95% CI = 1.13-2.61；p = 0.01）。农村地区的孕妇比首都地区的孕妇更容易患上癫痫症（OR = 1.55；95% CI = 1.12-2.14；p<0.01）。
阿拉戈斯州 PWWE 的社会人口学特征以棕色皮肤、单身、家庭主妇和文盲为主，且大多数人居住在该州内陆地区。产科数据显示剖宫产和流产的发生率较高。
