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HIV 感染者在 COVID-19 大流行期间的生活方式和抗逆转录病毒药物的依从性。

Lifestyle and adherence to antiretrovirals in people with HIV in the COVID-19 pandemic.

机构信息

Universidade Federal do Ceará. Fortaleza, Ceará, Brazil.

Universidade Estadual do Ceará. Fortaleza, Ceará, Brazil.

出版信息

Rev Bras Enferm. 2022 Jul 18;75Suppl 2(Suppl 2):e20210644. doi: 10.1590/0034-7167-2021-0644. eCollection 2022.

Abstract

OBJECTIVES

to assess the lifestyle and adherence to antiretrovirals in people living with HIV (PLHIV) in the COVID-19 pandemic.

METHODS

a cross-sectional study, through telephone interview to 150 patients, using a sociodemographic, epidemiological and clinical form, and questionnaires to assess lifestyle profile and adherence to antiretrovirals. Statistics analysis used Fisher's exact test, odds ratio and 95% confidence interval.

RESULTS

most patients had a satisfactory lifestyle (121; 80.7%) and adequate adherence to antiretrovirals (133; 88.7%). All were in social isolation, without follow-up appointments, with access to the health service only to receive antiretrovirals, and 16 (10.7%) had COVID-19 infection. Evangelicals (p=0.002), Spiritists (p=0.045), patients using atazanavir (p=0.0001) and ritonavir (p=0.002) had a more unsatisfactory lifestyle. Adherence to antiretrovirals was more inadequate in female patients (p=0.009), with two (p=0.004) and three or more children (p=0.006), retired (p=0.029), with serodiscordant partner (p=0.046) and diagnosis time of 5 to 10 years (p=0.027).

CONCLUSIONS

the most PLHIV had a satisfactory lifestyle and adequate adherence to antiretrovirals, but some groups needed intervention to improve medication adherence and lifestyle.

摘要

目的

评估 COVID-19 大流行期间艾滋病毒感染者(PLHIV)的生活方式和抗逆转录病毒药物依从性。

方法

这是一项横断面研究,通过电话访谈 150 名患者,使用社会人口统计学、流行病学和临床表格以及评估生活方式概况和抗逆转录病毒药物依从性的问卷。统计分析采用 Fisher 确切检验、比值比和 95%置信区间。

结果

大多数患者的生活方式令人满意(121 人;80.7%),抗逆转录病毒药物依从性良好(133 人;88.7%)。所有人都处于社会隔离状态,没有预约随访,只能获得抗逆转录病毒药物,16 人(10.7%)感染了 COVID-19。福音派(p=0.002)、巫师(p=0.045)、使用阿扎那韦(p=0.0001)和利托那韦(p=0.002)的患者生活方式更差。女性患者(p=0.009)、有两个(p=0.004)或三个以上孩子(p=0.006)、退休(p=0.029)、性伴侣不一致(p=0.046)和诊断时间为 5 至 10 年(p=0.027)的患者,抗逆转录病毒药物依从性更差。

结论

大多数 PLHIV 的生活方式令人满意,抗逆转录病毒药物依从性良好,但一些群体需要干预以提高药物依从性和改善生活方式。

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