Koros A M, Szulman A E, Hamill E C, Merchant B
Vox Sang. 1978;35(4):234-40. doi: 10.1111/j.1423-0410.1978.tb02927.x.
Lymphoid tissues from 24 human fetuses were assayed for hemolytic plaque-forming cells (PFC) against a variety of erythrocyte targets. PFC against maternal and other erythrocyte antigens were commonly detected in human fetal liver, lymph nodes, spleen, or thymus as early as 16 weeks gestation and were usually more abundant in liver than in spleen after 16 weeks gestation. These data corroborate studies from other laboratories which indicate that human fetuses develop some forms of immunocompetence very early during gestation.
对来自24例人类胎儿的淋巴组织进行检测，以确定针对多种红细胞靶标的溶血空斑形成细胞（PFC）。早在妊娠16周时，在人类胎儿肝脏、淋巴结、脾脏或胸腺中通常就能检测到针对母体和其他红细胞抗原的PFC，且在妊娠16周后，肝脏中的PFC通常比脾脏中的更丰富。这些数据证实了其他实验室的研究结果，即人类胎儿在妊娠早期就发展出了某些形式的免疫能力。
