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[新型冠状病毒肺炎疫苗诱导的血栓形成伴血小板减少综合征]

[COVID-19 Vaccine-Induced Thrombosis with Thrombocytopenia Syndrome].

作者信息

Yagita Yoshiki

机构信息

Department of Stroke Medicine, Kawasaki Medical School.

出版信息

Brain Nerve. 2022 Jul;74(7):905-909. doi: 10.11477/mf.1416202146.

Abstract

Thrombosis with thrombocytopenia syndrome (TTS) induced by the coronavirus disease 2019 vaccine is characterized by thrombocytopenia and thrombosis. Positivity for the anti-platelet factor 4-antibody is related to TTS pathophysiology, similar to heparin-induced thrombocytopenia. Although TTS is very rare, with an incidence of almost 1/100,000 cases, physicians need to keep in mind this adverse reaction that can lead to serious symptoms and death. Prompt treatment should be initiated in cases of suspected TTS.

摘要

2019冠状病毒病疫苗诱导的血栓形成伴血小板减少综合征(TTS)的特征是血小板减少和血栓形成。抗血小板因子4抗体阳性与TTS的病理生理学有关,类似于肝素诱导的血小板减少症。尽管TTS非常罕见,发病率几乎为十万分之一,但医生需要牢记这种可能导致严重症状和死亡的不良反应。疑似TTS病例应立即开始治疗。

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