Department of Infectious Diseases, CHU Besancon, Besancon, 25000, France.
Department of Bacteriology, CHU Besancon, Besancon, 25000, France.
Future Microbiol. 2022 Sep;17:1115-1124. doi: 10.2217/fmb-2021-0310. Epub 2022 Jul 21.
To describe the number of prosthetic joint infections (PJIs) with late documentation and to identify associated factors. Bacterial PJIs with surgical management between November 2015 and November 2019 in a French center were analyzed. Results of short (72 h) and late culture (at 14 days) were analyzed. A total of 160 PJIs were reported with 215 bacteria. Twenty-nine patients had late documentation (18.1%). The bacteria most involved were coagulase-negative staphylococci and spp. (60%). In multivariate analysis, late chronic PJI (odds ratio = 2.47) and antibiotic therapy before surgery (odds ratio = 3.13) were associated with late-documented infection. A better knowledge of the factors associated with late-documented infections is essential in order to simplify antibiotic treatment at the appropriate time.
描述假体关节感染（PJI）的迟发性记录数量，并确定相关因素。对 2015 年 11 月至 2019 年 11 月期间法国中心接受手术治疗的细菌性 PJI 进行了分析。分析了短期（72 小时）和晚期（14 天）培养的结果。共报告了 160 例 PJI，涉及 215 种细菌。29 例患者有迟发性记录（18.1%）。最常见的细菌是凝固酶阴性葡萄球菌和 spp.（60%）。多变量分析显示，迟发性慢性 PJI（比值比=2.47）和手术前抗生素治疗（比值比=3.13）与迟发性感染有关。为了在适当的时间简化抗生素治疗，了解与迟发性记录感染相关的因素至关重要。
