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接受颈椎后路椎板切除并器械融合术与颈椎后路单开门椎管扩大成形重建术患者的术后阿片类药物使用情况及处方模式

Postoperative Opioid Use and Prescribing Patterns among Patients Undergoing Cervical Laminectomy with Instrumented Fusion versus Cervical Laminoplasty with Reconstruction.

作者信息

Shankar Dhruv S, Kim Jinseong, Bienstock Dennis M, Gao Michael, Lee Yunsoo, Zubizarreta Nicole J, Poeran Jashvant, Lin James D, Chaudhary Saad B, Hecht Andrew C

机构信息

Leni & Peter May Department of Orthopaedics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Global Spine J. 2024 Mar;14(2):561-567. doi: 10.1177/21925682221116825. Epub 2022 Jul 21.

Abstract

STUDY DESIGN

Retrospective cohort study.

OBJECTIVE

To compare patterns in opioid usage and prescriptions between patients who undergo cervical laminectomy with instrumented fusion (LF) vs cervical laminoplasty with reconstruction (LP) within single surgeon and national database cohorts.

METHODS

We identified patients with cervical myelopathy undergoing primary LF or LP in both a single-surgeon series cohort (2004-2018) and a nationally representative cohort drawn from the IBM Marketscan database (2014-2016). We recorded opioid usage within 6 months of surgery and identified differences in unadjusted opioid use rates between LF and LP patients. Multivariable logistic regression was used to evaluate the association between procedure type and postoperative opioid use.

RESULTS

Without adjusting for covariates, LF patients had a higher rate of 6-month opioid use in the single-surgeon cohort (15.7% vs 5.1%, = .02). After adjusting for covariates, LF patients had higher odds of 6-month postoperative opioid use (OR 2.8 [95% CI 1.0-7.7], = .04). In the national cohort, without adjusting for covariates, there was no significant difference in 6-month opioid use between LF and LP patients. Even after adjusting for covariates, we found no significant difference in odds.

CONCLUSIONS

Findings from a single-surgeon cohort reveal that LF is associated with a higher rate of 6-month opioid use than LP. This is at odds with findings from a national database cohort, which suggested that LP and LF patients have similar rates of opioid usage at 6-months postoperatively. To prevent overuse of narcotics, surgeons must consider the distinct pain requirements associated with different procedures even in treatment of the same condition.

摘要

研究设计

回顾性队列研究。

目的

比较在单一外科医生和国家数据库队列中,接受颈椎椎板切除并器械融合术(LF)与颈椎椎板成形术并重建术(LP)的患者之间阿片类药物使用和处方模式。

方法

我们在一个单一外科医生系列队列(2004 - 2018年)和一个从IBM Marketscan数据库选取的具有全国代表性的队列(2014 - 2016年)中,识别出接受初次LF或LP的脊髓型颈椎病患者。我们记录了手术后6个月内的阿片类药物使用情况,并确定LF和LP患者之间未调整的阿片类药物使用率差异。使用多变量逻辑回归来评估手术类型与术后阿片类药物使用之间的关联。

结果

在未对协变量进行调整的情况下,单一外科医生队列中LF患者6个月阿片类药物使用率更高(15.7%对5.1%,P = 0.02)。在对协变量进行调整后,LF患者术后6个月使用阿片类药物的几率更高(比值比2.8 [95%置信区间1.0 - 7. seven],P = 0.04)。在全国队列中,未对协变量进行调整时,LF和LP患者6个月阿片类药物使用情况无显著差异。即使在对协变量进行调整后,我们也未发现几率有显著差异。

结论

单一外科医生队列的研究结果显示,LF与6个月阿片类药物使用率高于LP相关。这与国家数据库队列的研究结果不一致,后者表明LP和LF患者术后6个月阿片类药物使用率相似。为防止麻醉药品的过度使用,即使在治疗相同病症时,外科医生也必须考虑不同手术相关的独特疼痛需求。

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