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《退行性颈椎脊髓病管理临床实践指南:引言、原理及范围》

A Clinical Practice Guideline for the Management of Degenerative Cervical Myelopathy: Introduction, Rationale, and Scope.

作者信息

Fehlings Michael G, Tetreault Lindsay A, Riew K Daniel, Middleton James W, Wang Jeffrey C

机构信息

Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.

University of Toronto, Toronto, Ontario, Canada.

出版信息

Global Spine J. 2017 Sep;7(3 Suppl):21S-27S. doi: 10.1177/2192568217703088. Epub 2017 Sep 5.

Abstract

Degenerative cervical myelopathy (DCM) is a progressive spine disease and the most common cause of spinal cord dysfunction in adults worldwide. Patients with DCM may present with common signs and symptoms of neurological dysfunction, such as paresthesia, abnormal gait, decreased hand dexterity, hyperreflexia, increased tone, and sensory dysfunction. Clinicians across several specialties encounter patients with DCM, including primary care physicians, rehabilitation specialists, therapists, rheumatologists, neurologists, and spinal surgeons. Currently, there are no guidelines that outline how to best manage patients with mild (defined as a modified Japanese Orthopedic Association (mJOA) score of 15-17), moderate (mJOA = 12-14), or severe (mJOA ≤ 11) myelopathy, or nonmyelopathic patients with evidence of cord compression. This guideline provides evidence-based recommendations to specify appropriate treatment strategies for these populations. The intent of our recommendations is to (1) help identify patients at high risk of neurological deterioration, (2) define the role of nonoperative and operative management in each patient population, and (3) determine which patients are most likely to benefit from surgical intervention. The ultimate goal of these guidelines is to improve outcomes and reduce morbidity in patients with DCM by promoting standardization of care and encouraging clinicians to make evidence-informed decisions.

摘要

退行性颈椎脊髓病(DCM)是一种进行性脊柱疾病,也是全球成年人脊髓功能障碍最常见的原因。DCM患者可能会出现神经功能障碍的常见体征和症状,如感觉异常、步态异常、手部灵活性下降、反射亢进、肌张力增加和感觉功能障碍。包括初级保健医生、康复专家、治疗师、风湿病学家、神经科医生和脊柱外科医生在内的多个专业的临床医生都会接诊DCM患者。目前,尚无指南概述如何最佳管理轻度(定义为改良日本骨科协会(mJOA)评分为15 - 17)、中度(mJOA = 12 - 14)或重度(mJOA≤11)脊髓病患者,或有脊髓压迫证据的非脊髓病患者。本指南提供基于证据的建议,以明确针对这些人群的适当治疗策略。我们建议的目的是:(1)帮助识别有神经功能恶化高风险的患者;(2)明确非手术和手术管理在各患者群体中的作用;(3)确定哪些患者最有可能从手术干预中获益。这些指南的最终目标是通过促进护理标准化并鼓励临床医生做出基于证据的决策,改善DCM患者的治疗效果并降低发病率。

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