Department of Histology and Embryology, Center for Biostructure Research, 37803Medical University of Warsaw, Warsaw, Poland.
Laboratory for Cell Research and Application, 37803Medical University of Warsaw, Warsaw, Poland.
Altern Lab Anim. 2022 Jul;50(4):275-281. doi: 10.1177/02611929221113976. Epub 2022 Jul 21.
Resources from biobanks and biorepositories, such as human samples, are of increasing interest to specialists in various fields. However, whilst biobanks provide a crucial service, their efficient and effective management can prove challenging. When establishing a biobank many factors should be considered, such as the need for appropriate infrastructure, equipment, financial support, and highly specialised and suitably qualified personnel. The number and qualifications of the necessary personnel depend both on the biobank's size and type - i.e. a biobank that is large and diversified in terms of the stored material should be organised differently to a small biorepository. The core of the biobank should be composed of highly trained personnel that closely co-operate with the general and quality control manager. Due to the large amount of data related to the samples, an IT specialist might be needed. In the case of large population biobanks, personnel responsible for patient recruitment, documentation handling, sample collection and distribution to the biobank would be necessary. Furthermore, staff responsible for the infrastructure are also highly important, as they are the first responders to failures that may be critical for the biobank functioning. Depending on the type and size of the biobank/biorepository, some responsibilities and tasks could potentially be combined. Nevertheless, highly trained personnel with clear and precisely defined duties are the key to the proper functioning of a biobank.
生物银行和生物库(如人类样本)的资源引起了各个领域专家的越来越多的关注。然而,虽然生物银行提供了至关重要的服务,但它们的有效管理可能具有挑战性。建立生物银行时,应考虑许多因素,例如适当的基础设施、设备、财务支持以及高度专业化和合格的人员的需求。必要人员的数量和资格既取决于生物银行的规模和类型——即,在存储材料方面规模大且多样化的生物银行的组织方式应与小型生物库不同。生物银行的核心应由与一般和质量控制经理密切合作的高度训练有素的人员组成。由于与样本相关的大量数据,可能需要一名 IT 专家。在大型人群生物银行的情况下,需要负责患者招募、文件处理、样本采集和分发给生物库的人员。此外,负责基础设施的人员也非常重要,因为他们是对可能对生物库功能至关重要的故障的第一响应者。根据生物库/生物库的类型和规模,一些责任和任务可能会合并。然而,具有明确和精确定义职责的高度训练有素的人员是生物库正常运行的关键。