Eric J. Topol is at Scripps Research, La Jolla, CA, USA. Email:
Akiko Iwasaki is in the Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA, and at Howard Hughes Medical Institute, Chevy Chase, MD, USA. Email:
Sci Immunol. 2022 Aug 12;7(74):eadd9947. doi: 10.1126/sciimmunol.add9947. Epub 2022 Aug 19.
Given the poor ability of intramuscular mRNA COVID-19 vaccines to induce robust immunity in the respiratory mucosa, a push for a nasal vaccine strategy is needed.
鉴于肌肉内 mRNA COVID-19 疫苗在呼吸道黏膜中诱导强大免疫的能力较差，需要推动鼻内疫苗策略。
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