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Reply to the Letter to the Editor: "Importance of nasal secretions in the evaluation of mucosal immunity elicited by mRNA BNT162b2 COVID-19 vaccine" by Francavilla B et al.: Lack of a strong oral mucosal immune response: rethinking the route of COVID-19 vaccine boost administration?

作者信息

Azzi Lorenzo, Dalla Gasperina Daniela, Accolla Roberto Sergio, Forlani Greta

机构信息

Azienda Socio Sanitaria Territoriale dei Sette Laghi, Department of Medicine and Surgery, University of Insubria, Varese, Italy.

Azienda Socio Sanitaria Territoriale dei Sette Laghi, Department of Medicine and Surgery, University of Insubria, Varese, Italy.

出版信息

EBioMedicine. 2022 May;79:104005. doi: 10.1016/j.ebiom.2022.104005. Epub 2022 Apr 15.

DOI:10.1016/j.ebiom.2022.104005
PMID:35436727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9010772/
Abstract
摘要

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Reply to the Letter to the Editor: "Importance of nasal secretions in the evaluation of mucosal immunity elicited by mRNA BNT162b2 COVID-19 vaccine" by Francavilla B et al.: Lack of a strong oral mucosal immune response: rethinking the route of COVID-19 vaccine boost administration?致编辑信的回复：弗朗卡维拉等人的《mRNA BNT162b2 COVID-19疫苗引发的黏膜免疫评估中鼻分泌物的重要性》：缺乏强烈的口腔黏膜免疫反应：重新思考COVID-19疫苗加强接种的途径？
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引用本文的文献

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Differentially induced immunity in buccal and nasal mucosae after vaccination for SARS-CoV-2: Prospects for mass scale immunity-screening in large populations.接种 SARS-CoV-2 疫苗后口腔和鼻腔黏膜的差异诱导免疫：大规模人群免疫筛查的前景。
Front Immunol. 2022 Nov 17;13:999693. doi: 10.3389/fimmu.2022.999693. eCollection 2022.
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The importance of booster vaccination in the context of Omicron wave.奥密克戎变异株流行背景下加强免疫的重要性。
Front Immunol. 2022 Sep 8;13:977972. doi: 10.3389/fimmu.2022.977972. eCollection 2022.

本文引用的文献

1
Importance of nasal secretions in the evaluation of mucosal immunity elicited by mRNA BNT162b2 COVID-19 Vaccine.鼻分泌物在评估mRNA BNT162b2新冠疫苗引发的黏膜免疫中的重要性。
EBioMedicine. 2022 May;79:104006. doi: 10.1016/j.ebiom.2022.104006. Epub 2022 Apr 14.
2
Intranasal COVID-19 vaccines: From bench to bed.鼻内 COVID-19 疫苗：从实验室到临床。
EBioMedicine. 2022 Feb;76:103841. doi: 10.1016/j.ebiom.2022.103841. Epub 2022 Jan 24.
3
Mucosal immune response in BNT162b2 COVID-19 vaccine recipients.BNT162b2 新冠疫苗接种者的黏膜免疫应答。
EBioMedicine. 2022 Jan;75:103788. doi: 10.1016/j.ebiom.2021.103788. Epub 2021 Dec 23.
4
Antibody Responses to SARS-CoV-2 mRNA Vaccines Are Detectable in Saliva.唾液中可检测到对SARS-CoV-2 mRNA疫苗的抗体反应。
Pathog Immun. 2021 Jun 7;6(1):116-134. doi: 10.20411/pai.v6i1.441. eCollection 2021.