Villegas-Belman Sergio, Esparza-Gallegos Thania Carolina, Lizalde-Moreno José Alfredo, Marquez-Romero Juan Manuel
Department of Emergency Medicine, Hospital MAC Aguascalientes, Aguascalientes, Mexico.
Department of Internal Medicine, Instituto Mexicano del Seguro Social, Aguascalientes, Mexico.
Clin Exp Emerg Med. 2022 Dec;9(4):373-376. doi: 10.15441/ceem.21.086. Epub 2022 Jul 22.
The use of extracts from the hawthorn plant as cardiovascular agents dates back to the 1st century; recently, they have also been made available online as weight loss aids. Herein, we present a case of intentional intoxication with hawthorn root extract (HRE) in an adult patient that resulted in death. A 20-year-old female patient, who was clinically diagnosed with depression, developed hypotension, bradycardia, and depressed consciousness after ingestion of this extract. An electrocardiogram recorded a sinus arrest with a slow nodal rhythm, which rapidly deteriorated, leading to cardiac arrest. This case report illustrates the potentially fatal consequences of HRE for which the constituents have not yet been characterized. All physicians, especially those in the emergency department, should be aware of the dangerous, even potentially fatal interactions of HRE with prescription medications.
将山楂植物提取物用作心血管药物可追溯到公元1世纪；最近，它们也在网上作为减肥辅助品出售。在此，我们报告一例成年患者因故意摄入山楂根提取物（HRE）而中毒死亡的病例。一名20岁临床诊断为抑郁症的女性患者，在摄入该提取物后出现低血压、心动过缓和意识不清。心电图显示窦性停搏伴缓慢的结性心律，病情迅速恶化，导致心脏骤停。本病例报告说明了尚未明确其成分的HRE可能产生的致命后果。所有医生，尤其是急诊科医生，都应意识到HRE与处方药之间危险甚至可能致命的相互作用。
