Toyono M, Kuronuma M, Kameyama L, Tsukamoto M, Yamakawa M, Suzuki K
Gan No Rinsho. 1987 Mar;33(3):265-8.
In 130 resected specimens of gastric cancer, CEA was stained by the enzyme labeled antibody method. The positive rate of CEA stain was 74.6% and higher in well differentiated adenocarcinoma, mucinous adenocarcinoma, and signet ring cell carcinoma. The positive rate was lower in poorly differentiated adenocarcinoma. The 5-year survival rate was higher in the CEA (-) group in stage II, and higher in the CEA (+) group in stage III (p less than 0.05) and stage IV. This suggests that the correlation of the CEA stain and the prognosis varies with the stage of cancer.
在130例胃癌切除标本中,采用酶标抗体法对癌胚抗原(CEA)进行染色。CEA染色阳性率为74.6%,高分化腺癌、黏液腺癌及印戒细胞癌的阳性率更高。低分化腺癌的阳性率较低。Ⅱ期CEA(-)组的5年生存率较高,Ⅲ期和Ⅳ期CEA(+)组的5年生存率较高(P<0.05)。这表明CEA染色与预后的相关性随癌症分期而异。