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[癌胚抗原(CEA)产生能力与胃癌预后的相关性]

[The correlation between the productive capacity of carcinoembryonic antigen (CEA) and prognosis in gastric cancer].

作者信息

Toyono M, Kuronuma M, Kameyama L, Tsukamoto M, Yamakawa M, Suzuki K

出版信息

Gan No Rinsho. 1987 Mar;33(3):265-8.

PMID:3586342
Abstract

In 130 resected specimens of gastric cancer, CEA was stained by the enzyme labeled antibody method. The positive rate of CEA stain was 74.6% and higher in well differentiated adenocarcinoma, mucinous adenocarcinoma, and signet ring cell carcinoma. The positive rate was lower in poorly differentiated adenocarcinoma. The 5-year survival rate was higher in the CEA (-) group in stage II, and higher in the CEA (+) group in stage III (p less than 0.05) and stage IV. This suggests that the correlation of the CEA stain and the prognosis varies with the stage of cancer.

摘要

在130例胃癌切除标本中,采用酶标抗体法对癌胚抗原(CEA)进行染色。CEA染色阳性率为74.6%,高分化腺癌、黏液腺癌及印戒细胞癌的阳性率更高。低分化腺癌的阳性率较低。Ⅱ期CEA(-)组的5年生存率较高,Ⅲ期和Ⅳ期CEA(+)组的5年生存率较高(P<0.05)。这表明CEA染色与预后的相关性随癌症分期而异。

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