Oh S, Tsuchiya E, Kitagawa T, Minami K, Matsubara T, Nakagawa K, Kinoshita I, Sugano H
Gan No Rinsho. 1987 Mar;33(3):293-9.
Two cases of spindle cell squamous carcinoma of the lung are presented. Both cases were female heavy smokers aged 73 and 55. The carcinomas, 7.5 and 6.0 cm in diameter respectively, were located at the peripheral portion of the right lower lung lobes. Direct invasion to the diaphragma and metastasis to the chest wall were observed in the first case but no metastasis was observed in the second case. Histologically, both carcinomas showed a biphasic appearance due to the presence of a squamous cell carcinoma component and a spindle cell sarcomatous component with marked cellular pleomorphism, but no neoplastic bone, cartilage or muscle. Transitional area of two components were seen in the second case.
本文报告两例肺梭形细胞鳞状癌。两例均为女性重度吸烟者，年龄分别为73岁和55岁。肿瘤直径分别为7.5厘米和6.0厘米，位于右下肺叶周边部。第一例可见肿瘤直接侵犯膈肌并转移至胸壁，而第二例未见转移。组织学上，两例肿瘤均呈双相表现，由鳞状细胞癌成分和梭形细胞肉瘤样成分构成，细胞异型性明显，但未见肿瘤性骨、软骨或肌肉成分。第二例可见两种成分的移行区。
