Xia Wangxiao, Jiang Hui, Guo Huifang, Liu Yaowen, Gou Xingchun
Shaanxi Key Laboratory of Brain Disorders,Institute of Basic Translational Medicine, Xi'an Medical University, Xi'an 710021, China.
College of Life Science, Hainan Normal University, Haikou 571158, China.
Gene. 2022 Oct 5;840:146733. doi: 10.1016/j.gene.2022.146733. Epub 2022 Jul 18.
The typical life cycle of the moon jellyfish (Aurelia aurita) includes the planula, polyp, strobila, ephyra, and medusa developmental stages. These stages exhibit huge differences in both external morphology and internal physiological functions. However, the gene co-expression network involved in these post-embryonic developmental processes has not been studied yet. Here, based on 15 RNA sequencing samples covering all five stages of the A. aurita life cycle, we systematically analyzed the gene co-expression network and obtained 35 relevant modules. Furthermore, we identified the highly correlated modules and hub genes for each stage. These hub genes are implicated to play important roles in the developmental processes of A. aurita, which should help improve our understanding of the jellyfish life cycle.
月亮水母（海月水母）的典型生命周期包括浮浪幼虫、水螅体、横裂体、碟状幼体和水母发育阶段。这些阶段在外部形态和内部生理功能上都表现出巨大差异。然而，参与这些胚胎后发育过程的基因共表达网络尚未得到研究。在此，基于涵盖海月水母生命周期所有五个阶段的15个RNA测序样本，我们系统地分析了基因共表达网络并获得了35个相关模块。此外，我们确定了每个阶段高度相关的模块和枢纽基因。这些枢纽基因被认为在海月水母的发育过程中发挥重要作用，这将有助于增进我们对水母生命周期的理解。
