Department of Obstetrics and Gynecology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, 400008, India.
Department of Radiology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, 400008, India.
Arch Gynecol Obstet. 2023 Jul;308(1):25-34. doi: 10.1007/s00404-022-06708-9. Epub 2022 Jul 21.
Congenital cervicovaginal agenesis (CVA) with functioning endometrium is an extremely rare mullerian anomaly. Genital tract patency and fertility preservation are the major challenges in cases of CVA. With the advances in surgical techniques, management has shifted from a radical approach-like hysterectomy towards a more conservative approach of uterine conservation.
In the present study, we report our experience in managing four cases of congenital CVA with complete vaginal atresia, which were treated with a simple minimally invasive vaginal approach for UVA without using graft for neovagina creation and studied the long-term anatomic and functional result of uterovestibular anastomosis (UVA) in patients with CVA. A literature review was performed for congenital complete vaginal atresia (≤ 2 cm blind vagina), with a functioning uterus. The experience and results of this 4-year study are in accordance with the prior studies with 97% (33/34) success rate, where vestibular mucosa was used for the UVA.
Findings of this study should encourage more gynaecologists to learn and recreate a complete vaginal approach, as no special surgical equipments are needed. Hysterectomy should only be reserved for cases, where repeated anastomosis attempts fail. This minimally invasive technique should be preferred over canalization procedures and graft, as it is associated with a higher success rate with least complications and recurrence. Conservative end-to-end anastomosis with a completely vaginal approach should be offered as the primary treatment option for CVA with total vaginal atresia.
先天性宫颈阴道发育不全(CVA)伴功能性子宫内膜是一种极为罕见的苗勒管畸形。生殖道通畅和生育力保存是 CVA 病例的主要挑战。随着手术技术的进步,治疗方法已从类似于子宫切除术的激进方法转变为更保守的子宫保留方法。
本研究报告了我们在处理 4 例先天性 CVA 伴完全阴道闭锁的经验,这些患者采用简单的微创阴道方法进行 UVA,而无需使用移植物来创建新阴道,并研究了 CVA 患者的子宫阴道吻合术(UVA)的长期解剖和功能结果。对先天性完全阴道闭锁(≤2cm 盲阴道)伴功能性子宫进行了文献复习。这项 4 年研究的经验和结果与先前研究一致,成功率为 97%(33/34),其中 UVA 采用了前庭黏膜。
本研究的结果应鼓励更多的妇科医生学习并重新开展完整的阴道入路,因为不需要特殊的手术设备。只有在反复吻合尝试失败的情况下才应保留子宫切除术。与管腔成形术和移植物相比,这种微创技术具有更高的成功率、更少的并发症和复发率,应优先选择。对于完全性阴道闭锁的 CVA,应将完全阴道入路的保守端端吻合作为首选治疗方法。