伽玛刀立体定向放射外科治疗复发性 Rathke 裂隙囊肿：病例报告及文献分析。
Stereotactic Radiosurgery with Gamma Knife in Recurrent Rathke's Cleft Cyst: Case Report and Literature Analysis.
机构信息
Department of Neurosurgery and Gamma Knife, A.S.S.T. Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Department of Radiotherapy, A.S.S.T. Grande Ospedale Metropolitano Niguarda, Milan, Italy.
出版信息
Neurol India. 2022 May-Jun;70(3):1260-1262. doi: 10.4103/0028-3886.349598.
BACKGROUND
Rathke's cleft cyst is a benign expansive lesion of the sella turcica. If related to clinical disorders, the patient needs surgical treatment.
OBJECTIVE
To demonstrate the efficacy of radiosurgery in the treatment of relapse of Rathke's cleft cyst as an alternative to surgery.
METHODS AND MATERIAL
The stereotactic radiosurgical treatment was performed at the Gamma Knife Center of the Niguarda Hospital in a patient with Rathke's cleft cyst subjected to two subsequent neurosurgical resections with early regrowth of the cyst. The cyst underwent radiosurgery with a prescription dose of 12 Gy at 50% (minimum dose 9.8, mean 17.3 and maximum 24.4).
RESULTS
Three years after stereotactic radiosurgical treatment the patient is asymptomatic and does not present disorders of the hypothalamic-pituitary axis or further visual alterations. The control MRI shows a reduction of the cyst's volume.
CONCLUSIONS
Stereotactic radiosurgery resulted in a reduction of the cyst's volume and avoided further recourse to surgery.
背景
Rathke 氏裂囊肿是鞍内的良性膨胀性病变。如果与临床疾病相关，患者需要手术治疗。
目的
证明放射外科治疗 Rathke 氏裂囊肿复发的疗效，作为手术的替代方法。
方法和材料
在 Niguarda 医院的伽玛刀中心对 Rathke 氏裂囊肿患者进行立体定向放射外科治疗，该患者曾接受过两次随后的神经外科切除术，但囊肿早期复发。囊肿接受了放射外科治疗，处方剂量为 12 Gy 时 50%（最小剂量 9.8，平均 17.3，最大 24.4）。
结果
立体定向放射外科治疗 3 年后，患者无症状，无下丘脑-垂体轴紊乱或进一步的视力改变。磁共振成像（MRI）检查显示囊肿体积缩小。
结论
立体定向放射外科治疗使囊肿体积缩小，避免了进一步的手术。
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