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衰弱在韩国独居老年人抑郁与跌倒关系中的中介作用

The Mediating Effect of Frailty in the Relationship between Depression and Falls among Older People Living Alone in Korea.

作者信息

Kim Yeon-Ha, Cho Chung-Min

机构信息

College of Nursing, Korea National University of Transportation, 61 Daehak-ro, Jeungpyeong-gun, Chungbuk, South Korea.

College of Nursing, Sungshin Women's University, Dobong-ro, Gangbuk-gu, Seoul, South Korea.

出版信息

Iran J Public Health. 2022 Mar;51(3):596-605. doi: 10.18502/ijph.v51i3.8936.

DOI:10.18502/ijph.v51i3.8936
PMID:35865060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9276589/
Abstract

BACKGROUND

We explored the potential mediating role of frailty in the relationship between depression and falls.

METHODS

The participants were 1,408 community-dwelling older people living alone in South Korea. The potential mediating role of frailty in the relationship between depression and falls was evaluated through univariate and multivariate logistic regression. Baron and Kenny's three-step criteria for mediation were used to examine the mediating effect.

RESULTS

Frailty fully mediated the association between severe depression and falls in univariate (t=11.58, <.05) and multivariate (t=10.42, <.05) analyses.

CONCLUSION

Frailty is a valuable target for fall interventions in severely depressed older people living alone.

摘要

背景

我们探讨了衰弱在抑郁症与跌倒之间关系中的潜在中介作用。

方法

研究对象为韩国1408名独居的社区老年人。通过单因素和多因素逻辑回归评估衰弱在抑郁症与跌倒关系中的潜在中介作用。采用Baron和Kenny的三步中介标准来检验中介效应。

结果

在单因素分析(t = 11.58,P <.05)和多因素分析(t = 10.42,P <.05)中,衰弱完全介导了重度抑郁症与跌倒之间的关联。

结论

对于独居的重度抑郁老年人,衰弱是跌倒干预的一个有价值的靶点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0378/9276589/2e0bb97b35f7/IJPH-51-596-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0378/9276589/273f988e0a74/IJPH-51-596-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0378/9276589/2e0bb97b35f7/IJPH-51-596-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0378/9276589/273f988e0a74/IJPH-51-596-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0378/9276589/2e0bb97b35f7/IJPH-51-596-g002.jpg

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本文引用的文献

1
Effects of a nutrition plus exercise programme on physical function in sarcopenic obese elderly people: study protocol for a randomised controlled trial.营养加运动计划对肥胖型肌少症老年人身体功能的影响:一项随机对照试验的研究方案
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Agreement between the frailty index and phenotype and their associations with falls and overnight hospitalizations.衰弱指数与衰弱表型之间的一致性及其与跌倒和夜间住院的关联。
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Depressive Symptoms and Orthostatic Hypotension Are Risk Factors for Unexplained Falls in Community-Living Older People.
抑郁症状和直立性低血压是社区居住的老年人不明原因跌倒的危险因素。
J Am Geriatr Soc. 2016 May;64(5):1073-8. doi: 10.1111/jgs.14104.
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Prevalence of Frailty and Aging-Related Health Conditions in Older Koreans in Rural Communities: a Cross-Sectional Analysis of the Aging Study of Pyeongchang Rural Area.韩国农村社区老年人衰弱及与衰老相关健康状况的患病率:对平昌农村地区老龄化研究的横断面分析
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English translation of the Kihon Checklist.基础检查表的英文翻译。
Geriatr Gerontol Int. 2015 Apr;15(4):518-9. doi: 10.1111/ggi.12397.
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Depression and Frailty in Late Life: Evidence for a Common Vulnerability.晚年的抑郁与衰弱:共同易损性的证据
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Frailty and falls among adult patients undergoing chronic hemodialysis: a prospective cohort study.成年慢性血液透析患者的衰弱与跌倒:一项前瞻性队列研究。
BMC Nephrol. 2013 Oct 16;14:224. doi: 10.1186/1471-2369-14-224.
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Distribution but not amount of protein intake is associated with frailty: a cross-sectional investigation in the region of Nürnberg.蛋白质摄入量的分布而非数量与衰弱相关:纽伦堡地区的一项横断面调查
Nutr J. 2013 Aug 5;12:109. doi: 10.1186/1475-2891-12-109.
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