Davoudi Zahra, Hallajnejad Mohammad, Jamali Elena, Honarvar Mohammadjavad
Department of Endocrinology Skull Base Research Center of Shahid Beheshti University of Medical Sciences Tehran Iran.
Department of Neurosurgery Skull Base Research Center of Shahid Beheshti University of Medical Sciences Tehran Iran.
Clin Case Rep. 2022 Jul 18;10(7):e6087. doi: 10.1002/ccr3.6087. eCollection 2022 Jul.
Refractory aggressive prolactinomas are detected after the unresponsiveness to conventional therapies. We report two cases that underwent temozolomide treatment and have been in near-complete remission ever since. We suggest the pathology techniques for earlier detection and, subsequently, treatment with temozolomide to reduce morbidities and better respond to therapy.
难治性侵袭性催乳素瘤是在对传统治疗无反应后被发现的。我们报告了两例接受替莫唑胺治疗且此后一直处于近乎完全缓解状态的病例。我们建议采用病理技术进行早期检测,随后使用替莫唑胺进行治疗,以降低发病率并更好地应对治疗。