Dorris Emma R, Maccarthy James, Simpson Ken, McCarthy Geraldine M
University College Dublin School of Medicine, University College Dublin, Dublin, Ireland.
Northeast Fibromyalgia Support Group, Duleek, Ireland.
Front Pain Res (Lausanne). 2022 Jul 5;3:926331. doi: 10.3389/fpain.2022.926331. eCollection 2022.
Environmental sensitivity is commonly reported by people with fibromyalgia syndrome. People living with fibromyalgia syndrome frequently report hypersensitivity to noxious and non-noxious sensations. To date, there has been little empirical validation of sensory disturbance to non-noxious triggers. Environmental sensitivity is used as a diagnostic feature only in Bennet's alternative criteria for diagnosis of fibromyalgia, where it was ranked the second most important of the components for diagnosis, after number of pain sites. The aim of this study was to use a validated sensory measure to determine if people with fibromyalgia have greater sensory disturbances compared to people with other chronic pain conditions.
This study used the Sensory Perception Quotient (SPQ) 92 question survey in adults with chronic pain conditions. A fibromyalgia group ( = 135) and a non-fibromyalgia chronic pain control group ( = 45) were recruited. All participants completed the SPQ as a self-report measure of sensory processing. In addition to the original SPQ scoring method, the Revised Scoring of the Sensory Perception Quotient (SPQ-RS) method was used to investigate self-reported hypersensitivity and hyposensitivity and the vision, hearing, taste, touch, and smell subscales. Chi-squared tests were used for categorical variables and Mann Whitney U, or Kruskal-Wallis H test were used to compare groups.
The fibromyalgia group reported significantly more sensitivity compared to the control group ( = 0.030). The fibromyalgia group reported significantly greater hypersensitivity ( = 0.038), but not more hyposensitivity ( = 0.723) compared to controls. The average fibromyalgia SPQ score (92.64 ± 23.33) was similar to that previously reported for adults with autism (92.95 ± 26.61). However, whereas adults with autism had broad range hypersensitivity, the fibromyalgia group reported significantly more hypersensitivity compared to the control group, but the range was restricted to vision ( = 0.033), smell ( = 0.049) and touch (0.040).
These findings demonstrate greater sensory hypersensitivity in people with fibromyalgia compared to people with other chronic pain disorders. Greater hypersensitivity was restricted to touch, vision, and smell, all of which have previously been demonstrated to crosstalk with nociception.
纤维肌痛综合征患者常报告有环境敏感性。纤维肌痛综合征患者经常报告对有害和无害感觉过敏。迄今为止，对无害刺激引起的感觉障碍几乎没有实证验证。环境敏感性仅在贝内特诊断纤维肌痛的替代标准中用作诊断特征，在该标准中，它在诊断要素中排名第二重要，仅次于疼痛部位数量。本研究的目的是使用经过验证的感觉测量方法，以确定纤维肌痛患者与其他慢性疼痛疾病患者相比是否有更大的感觉障碍。
本研究对患有慢性疼痛疾病的成年人使用了感觉知觉商数（SPQ）92题调查问卷。招募了一个纤维肌痛组（n = 135）和一个非纤维肌痛慢性疼痛对照组（n = 45）。所有参与者都完成了SPQ，作为感觉处理的自我报告测量。除了原始的SPQ评分方法外，还使用了感觉知觉商数修订评分（SPQ-RS）方法来调查自我报告的过敏和感觉减退以及视觉、听觉、味觉、触觉和嗅觉子量表。卡方检验用于分类变量，曼-惠特尼U检验或克鲁斯卡尔-沃利斯H检验用于比较组间差异。
与对照组相比，纤维肌痛组报告的敏感性明显更高（P = 0.030）。与对照组相比，纤维肌痛组报告的过敏明显更严重（P = 0.038），但感觉减退并不更严重（P = 0.723）。纤维肌痛组的平均SPQ评分（92.64±23.33）与先前报道的自闭症成年人的评分（92.95±26.61）相似。然而，自闭症成年人有广泛的过敏，而纤维肌痛组与对照组相比报告的过敏明显更多，但范围仅限于视觉（P = 0.033）、嗅觉（P = 0.049）和触觉（P = 0.040）。
这些发现表明，与其他慢性疼痛疾病患者相比，纤维肌痛患者有更大的感觉过敏。更大的过敏仅限于触觉、视觉和嗅觉，所有这些先前已被证明与伤害感受相互影响。
