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Effect of epigenetic treatment on SST expression in neuroendocrine tumour patients.

作者信息

Refardt Julie, Klomp Maria J, van Koetsveld Peter M, Dogan Fadime, Konijnenberg Mark, Brabander Tessa, Feelders Richard A, de Herder Wouter W, Hofland Leo J, Hofland Johannes

机构信息

ENETS Center of Excellence, Department of Internal Medicine, Section of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands.

ENETS Center of Excellence, Department of Endocrinology, University Hospital Basel, Basel, Switzerland.

出版信息

Clin Transl Med. 2022 Jul;12(7):e957. doi: 10.1002/ctm2.957.

DOI:10.1002/ctm2.957
PMID:35866246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9304941/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4344/9304941/44381eb1406b/CTM2-12-e957-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4344/9304941/d9ecdb7c2fee/CTM2-12-e957-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4344/9304941/44381eb1406b/CTM2-12-e957-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4344/9304941/d9ecdb7c2fee/CTM2-12-e957-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4344/9304941/44381eb1406b/CTM2-12-e957-g001.jpg

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Theranostics. 2024 Jan 1;14(1):17-32. doi: 10.7150/thno.87345. eCollection 2024.
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The role of DNA methylation in human pancreatic neuroendocrine tumours.DNA甲基化在人类胰腺神经内分泌肿瘤中的作用。
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Epigenetic regulation of SST expression in small intestinal neuroendocrine tumors.

本文引用的文献

1
Comparing the Effect of Multiple Histone Deacetylase Inhibitors on SSTR2 Expression and [In]In-DOTATATE Uptake in NET Cells.比较多种组蛋白去乙酰化酶抑制剂对神经内分泌肿瘤细胞中生长抑素受体2(SSTR2)表达及[铟-111]依替膦酸([In]In-DOTATATE)摄取的影响。
Cancers (Basel). 2021 Sep 29;13(19):4905. doi: 10.3390/cancers13194905.
2
Potential for Increasing Uptake of Radiolabeled Ga-DOTATOC and I-MIBG in Patients with Midgut Neuroendocrine Tumors Using a Histone Deacetylase Inhibitor Vorinostat.使用组蛋白去乙酰化酶抑制剂伏立诺他增加中肠神经内分泌肿瘤患者放射性标记 Ga-DOTATOC 和 I-MIBG 的摄取的潜力。
Cancer Biother Radiopharm. 2021 Oct;36(8):632-641. doi: 10.1089/cbr.2020.4633. Epub 2021 Jul 12.
3
小肠神经内分泌肿瘤中 SST 表达的表观遗传调控。
Front Endocrinol (Lausanne). 2023 May 8;14:1184436. doi: 10.3389/fendo.2023.1184436. eCollection 2023.
4
Up-Regulation of PSMA Expression In Vitro as Potential Application in Prostate Cancer Therapy.前列腺特异性膜抗原(PSMA)体外表达上调在前列腺癌治疗中的潜在应用
Pharmaceuticals (Basel). 2023 Apr 4;16(4):538. doi: 10.3390/ph16040538.
5
Epigenetic drugs in somatostatin type 2 receptor radionuclide theranostics and radiation transcriptomics in mouse pheochromocytoma models.在生长抑素 2 型受体放射性核素治疗学和小鼠嗜铬细胞瘤模型中的辐射转录组学中应用表观遗传药物。
Theranostics. 2023 Jan 1;13(1):278-294. doi: 10.7150/thno.77918. eCollection 2023.
6
Peptide Receptor Radionuclide Therapy.肽受体放射性核素治疗。
J Clin Endocrinol Metab. 2022 Nov 25;107(12):3199-3208. doi: 10.1210/clinem/dgac574.
Overcoming nephrotoxicity in peptide receptor radionuclide therapy using [Lu]Lu-DOTA-TATE for the treatment of neuroendocrine tumours.
使用 [Lu]Lu-DOTA-TATE 克服肽受体放射性核素治疗中的肾毒性,用于治疗神经内分泌肿瘤。
Nucl Med Biol. 2021 Nov-Dec;102-103:1-11. doi: 10.1016/j.nucmedbio.2021.06.006. Epub 2021 Jul 1.
4
Inferior outcome of neuroendocrine tumor patients negative on somatostatin receptor imaging.生长抑素受体显像阴性的神经内分泌肿瘤患者的预后较差。
Endocr Relat Cancer. 2020 Nov;27(11):615-624. doi: 10.1530/ERC-20-0340.
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Epidrug-induced upregulation of functional somatostatin type 2 receptors in human pancreatic neuroendocrine tumor cells.表皮生长因子诱导人胰腺神经内分泌肿瘤细胞中功能性生长抑素2型受体上调。
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Upregulation of Key Molecules for Targeted Imaging and Therapy.上调靶向成像和治疗的关键分子。
J Nucl Med. 2016 Nov;57(11):1805-1810. doi: 10.2967/jnumed.115.165092. Epub 2016 Jun 30.
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Hydralazine-valproate: a repositioned drug combination for the epigenetic therapy of cancer.肼屈嗪-丙戊酸盐:一种用于癌症表观遗传治疗的重新定位的药物组合。
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BMC Cancer. 2005 Apr 29;5:44. doi: 10.1186/1471-2407-5-44.