Goldstein J, Avinoah I, Lifshitz T
J Surg Oncol. 1987 Jun;35(2):124-8. doi: 10.1002/jso.2930350213.
Neoplastic proliferation of the meibomian glands is most often characterized by a tarsal tumor of the eyelid conjunctiva, having the clinical appearance of a chalazion. As such, the tumor is frequently not recognized as a neoplasm and is treated conservatively as an inflammatory lesion. A protracted clinical course combined with repeated surgical excisions typify this slow-growing tumor of sebaceous gland cells. In addition to the usual features of polygonal cell shape, abundant cytoplasm, and numerous fat vacuoles, we describe the presence of a peculiar nuclear inclusion seen only in the parenchymal cells of this tumor, and having the appearance of concentric layers of electron-dense material surrounding an opaque electron lucent core.
睑板腺的肿瘤性增生最常表现为眼睑结膜的睑板肿瘤，临床外观类似睑板腺囊肿。因此，该肿瘤常未被识别为肿瘤，而是作为炎性病变进行保守治疗。这种皮脂腺细胞的生长缓慢的肿瘤典型特征是病程迁延并多次手术切除。除了多边形细胞形态、丰富的细胞质和大量脂肪空泡等常见特征外，我们还描述了一种仅在该肿瘤实质细胞中可见的特殊核内包涵体，其外观为围绕不透明电子透亮核心的同心层状电子致密物质。
