Department of Otolaryngology-Head and Neck Surgery, San Raffaele Scientific Institute, Vita-Salute University, Via Olgettina 60, 20132, Milan, Italy.
Ann Surg Oncol. 2022 Dec;29(13):8361. doi: 10.1245/s10434-022-12171-2. Epub 2022 Jul 22.
Facial artery myomucosal flap (FAMM) is an intraoral flap pedicled on facial artery used for reconstruction of oral/oropharyngeal defects. Careful assessment of perfusion is essential to avoid flap necrosis, and several options are used for this purpose. Among these, indocyanine green (ICG) fluorescence video-angiography (ICG-VA) represents an innovative tool whose adoption in flap surgery is still at its early days. METHODS: In this multimedia article, we described the use of ICG-VA for perfusion assessment of a FAMM flap harvested for reconstruction of oral lining after ablation of a cT2cN0 floor-of-mouth (FOM) cancer. The use of ICG-VA was aimed at defining ischemic areas on the flap according to a flap-to-normal mucosa ICG ratio.
After transoral excision of the FOM cancer and subsequent harvesting of a FAMM flap, we used ICG-VA to intraoperatively assess its perfusion. The degree of flap perfusion was expressed point-by-point through flap-to-normal mucosa ICG ratio (percentage); a value of 25-27% was considered as threshold for ischemia. Perfusion was documented both with white light modality with "overlay fluorescence" and "black and white SPY fluorescence mode" designed to increase the sensitivity of ICG detection. Small, ischemic areas were detected in the distal part of the flap and were trimmed. At the end of the procedure, an adequate perfusion was evident throughout the whole flap, allowing its safe insetting for left FOM reconstruction. Postoperative course was uneventful.
ICG-VA represents a reliable tool for intraoperative detection-and trimming-of ischemic areas on reconstructive flaps.
面动脉肌黏膜瓣(FAMM)是一种以面动脉为蒂的口腔内瓣,用于重建口腔/口咽缺损。为避免皮瓣坏死,需要仔细评估灌注情况,为此有几种选择。其中,吲哚菁绿(ICG)荧光血管造影(ICG-VA)是一种创新工具,其在皮瓣手术中的应用仍处于早期阶段。
在本篇多媒体文章中,我们描述了使用 ICG-VA 评估为修复口底(FOM)癌症消融后口腔衬里而采集的 FAMM 皮瓣的灌注情况。根据皮瓣与正常黏膜 ICG 比值,使用 ICG-VA 来定义皮瓣上的缺血区域。
在经口切除 FOM 癌症并随后采集 FAMM 皮瓣后,我们在术中使用 ICG-VA 来评估其灌注情况。通过皮瓣与正常黏膜 ICG 比值(百分比)逐点表达皮瓣灌注程度;25-27%的值被认为是缺血的阈值。通过白光模式和设计用于提高 ICG 检测灵敏度的“叠加荧光”和“黑白 SPY 荧光模式”来记录灌注情况。在皮瓣的远端检测到小的缺血区域,并进行修剪。在手术结束时,整个皮瓣的灌注情况良好,允许其安全地用于左侧 FOM 重建。术后过程顺利。
ICG-VA 是一种用于术中检测和修剪重建皮瓣缺血区域的可靠工具。