Department of Medical Science, University of Ferrara, Via Aldo Moro 8, 44124, Ferrara, ITALY.
Azienda Ospedaliero-Universitaria di Ferrara, Via Aldo Moro 8, 44124, Ferrara, ITALY.
Clin Geriatr Med. 2022 Aug;38(3):483-500. doi: 10.1016/j.cger.2022.03.001. Epub 2022 Mar 21.
Covid-19 clinical presentation is extremely heterogenous, especially in older patients due to the possible presence of atypical symptoms, such as delirium, hyporexia and falls. The clinical characteristics at onset are influenced by the presence of common health-related conditions in older people, such as comorbidity, disability and frailty, and not simply by chronological age. Few studies investigated the tendency of Covid-19 symptoms to aggregate in cluster and the use of cluster approach might better describe the clinical complexity of the acute disease. Concerning the prognostic significance of Covid-19 clinical presentation in older people, the available literature still provides discordant results.
Covid-19 的临床表现极其多样,尤其是在老年患者中,可能存在不典型症状,如谵妄、食欲减退和跌倒。发病时的临床特征受老年人常见健康相关状况的影响,如合并症、残疾和虚弱,而不仅仅受年龄的影响。很少有研究调查 Covid-19 症状聚集在簇中的趋势,使用聚类方法可能更好地描述急性疾病的临床复杂性。关于老年人中 Covid-19 临床表现的预后意义,现有文献仍提供不一致的结果。