Gekht B M, Kuralesin M G, Gnezditskaia E V, Shagal D I
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(8):1129-34.
With the aid of an indirect method of immunofluorenscence in the process of a study of 65 blood sera of patients with myasthenia, the authors, demonstrated significant prevalence of antibodies titres to myoid cells and to an epithelial thymus reticulum (especialey in patients with thymomas) in comparison with normals. These data my indicate an autoimmune character of myasthenia. A positive effect of hormonal therapy was accompanied by a distinct drop in the level of antibodies in patients with myasthenia which permits to assume a certain connection between hormonotherapy and its influence on the autoimmune processes.
在对65例重症肌无力患者血清进行研究的过程中,作者借助间接免疫荧光法,发现与正常人相比,重症肌无力患者血清中抗肌样细胞和抗胸腺上皮网状细胞抗体滴度显著升高(尤其是胸腺瘤患者)。这些数据表明重症肌无力具有自身免疫性。激素治疗的积极效果伴随着重症肌无力患者抗体水平的明显下降,这使得人们可以推测激素治疗与其对自身免疫过程的影响之间存在某种联系。