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培训过的重症监护专家覆盖对院内心肺复苏后生存结局的影响:韩国全国队列研究。

Impact of trained intensivist coverage on survival outcomes after in-hospital cardiopulmonary resuscitation: A nationwide cohort study in South Korea.

机构信息

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea; Department of Anesthesiology and Pain Medicine, College of Medicine, Seoul National University, Seoul, South Korea.

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

出版信息

Resuscitation. 2022 Sep;178:69-77. doi: 10.1016/j.resuscitation.2022.07.022. Epub 2022 Jul 21.

Abstract

AIM

We aimed to investigate whether trained intensivist coverage affects survival outcomes following in-hospital cardiopulmonary resuscitation (ICPR) for in-hospital cardiac arrest (IHCA).

METHODS

All adult patients who received ICPR for IHCA between January 1, 2016 and December 31, 2019 in South Korea were included. Patients who received ICPR in hospitals with trained intensivist coverage for ICU staffing were defined as the intensivist group, whereas other patients were considered the non-intensivist group.

RESULTS

In total 68,286 adult patients (36,025 [52.8%] in the intensivist group and 32,261 [47.2%] in the non-intensivist group) were included in the analysis. After propensity score (PS) matching 40,988 patients (20,494 in each group) were included. In logistic regression after PS matching, the intensivist group showed a 17% (odds ratio: 1.17; 95% confidence interval [CI]: 1.12-1.22; P < 0.001) higher live discharge rate after ICPR than the non-intensivist group. In Cox regression after PS matching, the 6-month and the 1-year mortality rates in the intensivist group after ICPR were 11% (hazard ratio [HR]: 0.89; 95% CI: 0.87-0.91; P < 0.001) and 10% (HR: 0.90; 95% CI: 0.88-0.92; P < 0.001) lower than those in the non-intensivist group, respectively. In Kaplan-Meir estimation the median survival time after ICPR in the intensivist group was 12.0 days (95% CI: 11.6-12.4) while that in the non-intensivist group was 8.0 days (95% CI: 7.7-8.3).

CONCLUSIONS

Trained intensivist coverage in the ICU was associated with improvements in both short and long-term survival outcomes after ICPR for IHCA.

摘要

目的

本研究旨在探讨 ICU 中经过培训的重症监护医生覆盖范围是否会影响院内心搏骤停(IHCA)后院内心肺复苏(ICPR)的生存结局。

方法

纳入 2016 年 1 月 1 日至 2019 年 12 月 31 日期间在韩国接受 ICPR 的所有成年 IHCA 患者。在 ICU 配备有经过培训的重症监护医生的医院接受 ICPR 的患者被定义为重症监护组,而在其他医院接受 ICPR 的患者被视为非重症监护组。

结果

共纳入 68286 名成年患者(重症监护组 36025 名[52.8%],非重症监护组 32261 名[47.2%])进行分析。经过倾向评分(PS)匹配后,纳入 40988 名患者(每组 20494 名)。在 PS 匹配后的逻辑回归中,重症监护组的 ICPR 后活出院率高出 17%(优势比:1.17;95%置信区间[CI]:1.12-1.22;P<0.001)。在 PS 匹配后的 Cox 回归中,重症监护组患者 ICPR 后 6 个月和 1 年的死亡率分别为 11%(风险比[HR]:0.89;95%CI:0.87-0.91;P<0.001)和 10%(HR:0.90;95%CI:0.88-0.92;P<0.001),低于非重症监护组。在 Kaplan-Meier 估计中,重症监护组患者 ICPR 后中位生存时间为 12.0 天(95%CI:11.6-12.4),而非重症监护组为 8.0 天(95%CI:7.7-8.3)。

结论

ICU 中经过培训的重症监护医生覆盖范围与 IHCA 后 ICPR 的短期和长期生存结局改善相关。

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