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COVID-19 morbidity decreases with tixagevimab-cilgavimab preexposure prophylaxis in kidney transplant recipient nonresponders or low-vaccine responders.

作者信息

Kaminski Hannah, Gigan Mickael, Vermorel Agathe, Charrier Manon, Guirle Laura, Jambon Frederic, Lacapère Arthur, Ménard Coline, Moreau Karine, Neau-Cransac Martine, Novion Marine, Pribat Frederique, Taton Benjamin, Borde Sébastien, Burguet Laure, Martinez Charlie, Jasiek Magali, D'Halluin Pauline, Lafon Marie-Edith, Merville Pierre, Couzi Lionel

机构信息

Department of Nephrology, Transplantation, Dialysis and Apheresis, Bordeaux University Hospital, Bordeaux, France.

Department of Pharmacy, Bordeaux University Hospital, Bordeaux, France.

出版信息

Kidney Int. 2022 Oct;102(4):936-938. doi: 10.1016/j.kint.2022.07.008. Epub 2022 Jul 20.

DOI:10.1016/j.kint.2022.07.008
PMID:35870641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9297679/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5734/9297679/6a1ac823d17c/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5734/9297679/6a1ac823d17c/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5734/9297679/6a1ac823d17c/gr1_lrg.jpg

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1
COVID-19 morbidity decreases with tixagevimab-cilgavimab preexposure prophylaxis in kidney transplant recipient nonresponders or low-vaccine responders.在肾移植受者无应答者或低疫苗应答者中,替沙格韦单抗-西加韦单抗暴露前预防可降低COVID-19发病率。
Kidney Int. 2022 Oct;102(4):936-938. doi: 10.1016/j.kint.2022.07.008. Epub 2022 Jul 20.
2
Tixagevimab/cilgavimab pre-exposure prophylaxis is associated with lower breakthrough infection risk in vaccinated solid organ transplant recipients during the omicron wave.替沙格韦单抗/西加韦单抗用于暴露前预防,可降低奥密克戎变异株流行期间接受疫苗接种的实体器官移植受者突破性感染的风险。
Am J Transplant. 2022 Dec;22(12):3130-3136. doi: 10.1111/ajt.17128. Epub 2022 Jul 1.
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Risk factors for breakthrough COVID-19 infections in solid organ transplant recipients receiving tixagevimab/cilgavimab for pre-exposure prophylaxis.接受替沙格韦单抗/西加韦单抗进行暴露前预防的实体器官移植受者中出现COVID-19突破性感染的风险因素。
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Pre-exposure prophylaxis with tixagevimab/cilgavimab for coronavirus disease 2019 (COVID-19) during the Omicron BA.5 wave at a single institution in Japan.在日本的一家机构中,针对奥密克戎 BA.5 波进行的 2019 年冠状病毒病(COVID-19)用替沙格韦单抗/西加韦单抗的预先暴露预防。
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Myalgia in liver transplant recipients after receiving tixagevimab/cilgavimab for pre-exposure prophylaxis of COVID-19: A case series.肝移植受者在接受 tixagevimab/cilgavimab 进行 COVID-19 暴露前预防后出现肌痛:病例系列研究。
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[Pharmacoeconomic evaluation of the tixagevimab and cilgavimab combination using for pre-exposure prophylaxis of COVID-19].替沙格韦单抗和西加韦单抗联合用于新型冠状病毒肺炎暴露前预防的药物经济学评价
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Front Transplant. 2025 Jun 10;4:1579226. doi: 10.3389/frtra.2025.1579226. eCollection 2025.
2
Unveiling protection: a meta-analysis of tixagevimab-cilgavimab prophylaxis in 28,950 transplant recipients and immunocompromised patients against COVID-19.揭示保护作用:对28950名移植受者和免疫功能低下患者使用替沙格韦单抗-西加韦单抗预防COVID-19的荟萃分析
Virol J. 2025 Jun 2;22(1):178. doi: 10.1186/s12985-025-02814-7.
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SARS-COV-2 Pre-Exposure Prophylaxis With Tixagevimab-Cilgavimab in Haematological, Immunocompromised Patients in the Omicron Era.
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Eur J Haematol. 2025 Apr;114(4):690-699. doi: 10.1111/ejh.14377. Epub 2025 Jan 6.
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Therapeutic Potential of Neutralizing Monoclonal Antibodies (nMAbs) against SARS-CoV-2 Omicron Variant.针对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)奥密克戎变种的中和单克隆抗体(nMAbs)的治疗潜力
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