Cheng Y R, Fontana R
Microbiologica. 1987 Apr;10(2):229-34.
The penicillin-binding proteins (PBPs) of Micromonospora were studied. Only one PBP (48,000 mol weight) was found in membranes isolated from primary mycelia, whereas three PBPs were observed in secondary mycelia and designated PBP 1 (89,000 mol weight), PBP2 (69,000) and PBP3 (48,000). Both the unique PBP produced by primary mycelia and PBP3 of secondary mycelia had the same affinity for penicillin which was higher than that of PBP2 and 3. The role of these proteins in the cell life cycle of Micromonospora is discussed.
对小单孢菌的青霉素结合蛋白（PBPs）进行了研究。在从初级菌丝体分离的膜中仅发现一种PBP（分子量48,000），而在次级菌丝体中观察到三种PBP，分别命名为PBP 1（分子量89,000）、PBP2（分子量69,000）和PBP3（分子量48,000）。初级菌丝体产生的独特PBP和次级菌丝体的PBP3对青霉素具有相同的亲和力，且高于PBP2和PBP3。讨论了这些蛋白质在小单孢菌细胞生命周期中的作用。
