Betz H
Acta Biol Med Ger. 1977;36(11-12):1525-30.
The role of protein degradation in cell and tissue differentiation has been investigated during the sporulation of Saccharomyces cerevisiae and during endplate formation in developing avian muscle. The results suggest that a variety of proteolytic processes as enzyme inactivation, degradation of mitochondrial membrane constituents and removal of embryonic cell surface proteins exert stringent controls over the sequence of differentiation in eukaryotic cells.
在酿酒酵母的孢子形成过程以及发育中的禽类肌肉终板形成过程中，人们研究了蛋白质降解在细胞和组织分化中的作用。结果表明，多种蛋白水解过程，如酶失活、线粒体膜成分降解以及胚胎细胞表面蛋白的去除，对真核细胞的分化顺序施加了严格的控制。
