使用骨髓闪烁扫描术改善转移性尤因肉瘤的检测。

Improved detection of metastatic Ewing's sarcoma with the use of bone marrow scintigraphy.

作者信息

Jones G R, Miller J H, White L, Laug W E, Shore N A

出版信息

Med Pediatr Oncol. 1987;15(2):78-81. doi: 10.1002/mpo.2950150206.

Abstract

Prognosis in Ewing's sarcoma is inversely related to the extent of the disease at the time of presentation. The most common sites of metastases are the lungs and skeleton. Bone marrow metastases may be present but clinically silent. We report the use of Technetium (Tc)-99m bone marrow scintigraphy to detect sites of marrow involvement by metastatic Ewing's sarcoma. This method of evaluation allowed identification of sites of involvement by Ewing's sarcoma that were not available by any other method of evaluation. In several instances, information provided by this method was pivotal in the management of these patients. Based on this small series of patients, bone marrow scintigraphy appears to be a sensitive modality in the detection of metastatic disease in patients with Ewing's sarcoma. Better understanding of the role of bone marrow scanning and its correlation with other diagnostic procedures in Ewing's sarcoma will require further study.

摘要

尤因肉瘤的预后与就诊时疾病的范围呈负相关。最常见的转移部位是肺和骨骼。骨髓转移可能存在，但临床上无症状。我们报告了使用锝（Tc）-99m骨髓闪烁显像术来检测转移性尤因肉瘤的骨髓受累部位。这种评估方法能够识别出通过任何其他评估方法都无法发现的尤因肉瘤受累部位。在多个病例中，该方法提供的信息对这些患者的治疗起到了关键作用。基于这一小系列患者，骨髓闪烁显像术似乎是检测尤因肉瘤患者转移性疾病的一种敏感方法。要更好地理解骨髓扫描在尤因肉瘤中的作用及其与其他诊断程序的相关性，还需要进一步研究。