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富血小板血浆在动物生殖医学中的应用:前景与展望。

Platelet-rich plasma in animal reproductive medicine: Prospective and applications.

机构信息

Research and Development Station for Cattle Breeding, Romanian Academy of Science, Holboca, Romania.

Swissgenetics, Zurich, Switzerland.

出版信息

Reprod Domest Anim. 2022 Nov;57(11):1287-1294. doi: 10.1111/rda.14213. Epub 2022 Aug 1.

DOI:10.1111/rda.14213
PMID:35871399
Abstract

Platelet-rich plasma (PRP) is the fraction of the plasma enriched with a platelet level above baseline, and it plays an essential role in tissue regeneration. The attention to PRP as unconventional therapy has increased during the past two decades. In animals, applications of PRP showed various degrees of success in a wide range of medical applications, from musculoskeletal injuries to ovarian insufficiency. Therapeutic applications with PRP in farm animals are still scarce, but the promising results offered by several studies are expected to trigger more interest in its application by both veterinarians and farmers. In this review, we highlight some efforts made in the field of animal reproduction regarding the use of PRP to potentiate the ovarian hypofunction, treat endometritis, improve the follicular development, oocyte competence and uterine environment for embryo implantation as well as restore testicular and erectile function in male, and as a treatment for mastitis.

摘要

富血小板血浆(PRP)是富含血小板水平高于基线的血浆部分,它在组织再生中起着至关重要的作用。在过去的二十年中,人们对 PRP 作为非传统疗法的关注日益增加。在动物中,PRP 的应用在从肌肉骨骼损伤到卵巢功能不全的广泛医学应用中取得了不同程度的成功。PRP 在农场动物中的治疗应用仍然很少,但几项研究提供的有希望的结果预计将引发兽医和农民对其应用的更多兴趣。在这篇综述中,我们强调了在动物繁殖领域为增强卵巢功能低下、治疗子宫内膜炎、改善卵泡发育、卵母细胞能力和子宫环境以利于胚胎着床以及恢复睾丸和勃起功能而使用 PRP 所做的一些努力,以及作为乳腺炎的治疗方法。

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Platelet-rich plasma in animal reproductive medicine: Prospective and applications.富血小板血浆在动物生殖医学中的应用:前景与展望。
Reprod Domest Anim. 2022 Nov;57(11):1287-1294. doi: 10.1111/rda.14213. Epub 2022 Aug 1.
2
A narrative review of platelet-rich plasma (PRP) in reproductive medicine.富含血小板血浆(PRP)在生殖医学中的应用:综述
J Assist Reprod Genet. 2021 May;38(5):1003-1012. doi: 10.1007/s10815-021-02146-9. Epub 2021 Mar 15.
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Preliminary report of intraovarian injections of autologous platelet-rich plasma (PRP) in extremely poor prognosis patients with only oocyte donation as alternative: a prospective cohort study.卵巢内注射自体富血小板血浆(PRP)用于预后极差且仅能选择卵母细胞捐赠患者的初步报告:一项前瞻性队列研究
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引用本文的文献

1
Thrombocytes and Platelet-Rich Plasma as Modulators of Reproduction and Fertility.血小板和富含血小板的血浆作为生殖和生育的调节剂。
Int J Mol Sci. 2023 Dec 11;24(24):17336. doi: 10.3390/ijms242417336.
2
Lyophilized equine platelet-rich plasma (L-GF) antagonize the Reproductive toxicity and oxidative stress Induced by Cyclophosphamide in female rats.冻干粉状马富血小板血浆(L-GF)拮抗环磷酰胺对雌性大鼠的生殖毒性和氧化应激。
J Ovarian Res. 2023 Apr 28;16(1):84. doi: 10.1186/s13048-023-01161-x.